Professor: Pediatrics, Anatomy & Neurobiology, Neurology, Physiology & Biophysics
Danette Shepard Professor of Neurological Sciences
Contact Information:
  • E-mail:
  • Office Location: Hewitt Hall, 3024; Medical Sciences 1, B151
  • Mailing Address:, University of California, Irvine; Medical Sciences I, ZOT 4475; Irvine, CA 92697-4475
  • Phone: 949-824-1063 or 949-824-6478
  • Fax: 949-824-1106

baramTallie Z. Baram, MD, PhD is a Professor of Pediatrics, Anatomy/Neurobiology, Neurology and Physiology/Biophysics at the University of California-Irvine, and the Danette Shepard Professor of Neurological Sciences. Baram is a child neurologist and developmental neuroscientist and who has been focusing her efforts on programming the developing brain as a result of early-life experiences. Baram’s group has studied this broad topic in two contexts: a. how early-life experiences including stress and maternal care influence resilience and vulnerability to cognitive and emotional disorders; b. how early life seizures, especially those associated with fever, can convert a normal brain into an epileptic one. Using rodent models and cutting-edge molecular, cellular epigenetic and imaging methods, Baram’s group has made enormous contributions to our understanding of the effects of early-life experience on normal brain function and the contributions of early-life adversity and seizures to neuropsychiatric disorders. Baram’s discoveries have been translational, providing the foundation of an FDA-approved therapy and of novel clinical imaging approaches.

Baram’s research contributions have been recognized by prestigious awards including the NIH NINDS Javits Merit Award, AES Basic Science Research Award, and the CNS Sachs Award, and she has chaired the NIH Developmental Brain Disorders study section. Baram has had a long commitment to mentoring. She is PI of one of two NIH funded T32s focused on epilepsy, and is mentor of several currently funded K awards. Baram’s numerous students from diverse backgrounds are now contributing independently to neuroscience research.


Education & Training:

Institution, Location Degree Year Awarded Field of Study
Tel-Aviv University, Israel BS 1973 Biology
Weizmann Institute of Science, Rehovot, Israel PhD 1978 Neuroscience
University of Miami, School of Medicine, Florida MD 1980 Medicine
Baylor College of Medicine, Houston, Texas Residency 1982 Pediatrics
Baylor College of Medicine, Houston, Texas Fellowship 1985 Child Neurology

Selected Honors and Awards:

  • 2013: Bernard Sachs Distinguished Award for Research, Child Neurology Society
  • 2011: Soriano Lectureship Award, Distinguished Honor of the American Neurological Association
  • 2010: Mentorship Award, UCI Alumni Association
  • 2009: Distinguished Award for Epilepsy Research, American Society of Pharmacology & Experimental Therapies
  • 2008: Distinguished Scholar Lectureship, Office of the President, University of California
  • 2006: Javits Merit Award, NIH National Institute of Neurologic Disorders and Stroke
  • 2005: Milken Research Recognition Award in Basic Sciences (Premier Honor), American Epilepsy Society
  • 2004-2006: Elected, American Epilepsy Society Executive Board
  • 2003: Research Initiative Award, American Epilepsy Society
  • 1999: Athalie Clarke Excellence in Research AwardUniversity of California at Irvine
  • 1995: Danette D. Shepard Endowed Chair in Neurological SciencesUniversity of California at Irvine
  • 1991: Young Investigator Research Award, American Epilepsy Society
  • 1988-1993: Career Development Research Award (K08), NIH National Institute of Neurologic Disorders and Stroke
  • 1978-1980: Kennedy Memorial Postdoctoral Award, Weizmann Institute of Science (Highest Graduate Award)
  • 1977: EMBO: Short Term International Research Award, J. Axelrod’s Lab, NIH, Bathesdaa
  • 1976-1977: Bloom Fellowship for Doctoral Studies, Life Sciences, Weizmann Institute of Science

Positions & Employment:

  • 1985-1987: Assistant Professor, Neurology, Neuro-oncology & Pediatrics; University of Texas & MD Anderson, Houston
  • 1987-1992: Assistant Professor, Neurology & Pediatrics; University of Southern California & Children’s Hospital, Los Angeles
  • 1992-1995: Associate Professor, Neurology & Pediatrics; USC and CHLA
  • 1995-            : Professor, Pediatrics, Anatomy/Neurobiology, Neurology; University of California at Irvine (UCI)
  • 2002-            : Founder and Director, UCI Epilepsy Research Center (EpiCenter)
  • 2010-            : Professor, Physiology & Biophysics, UCI
  • 2013-            : Director, Conte Center @ UCI

Selected Professional Leadership and Contributions:

  • Chair, NIH-CSR Developmental Brain Disorders (DBD) study section (Fall 2011-2013)
  • Executive Board, Hewitt Foundation for Biomedical Research (2014-)
  • NIH NIMH member, Study Section for Conte Center Review (2013)
  • Department of Defense, Member, Review panel: Medical research grant pre-applications, 2014
  • NIH-NINDS Neuroscience (NST) study section, member (1998-2002)
  • NIH CSR Study Sections, ad hoc Member DBD, NNB, SRB-M, others
  • NIH NINDS: Biomarkers in Epileptogenesis workshop session co-organizer (2006); Models for Pediatric Epilepsies (2004, 2006)
  • NIH/AES Taskforce on AED development; Benchmark steward (2003-2008)
  • Executive Board, American Epilepsy Society: (2004-2006);
  • American Academy of Neurology, Penry-Dreyfuss Award committee (2001-2006)
  • Science Advisory Board, Epilepsy Foundation of America (2001-5); Research Council (2006-2010)
  • Chair, Scientific Committee, Pediatric Partnership for Epilepsy Research. (2006-2010)
  • Chair, Executive Board of Trustees, American Epilepsy Lennox & Lombroso Research Trust (2010-)
  • Child Neurology Society committees: Science (91-93; 97-99); Chair, Membership (93-95), Strategic Planning (2008-10)

Editorial Boards (Current):

  • Associate Editor:
    • Journal of Neuroscience-2014-2017
  • Reviewing Editor:
    • eNeuro, 2014-
    • Annals of Neurology, 2005-
    • Neurobiology of Stress, 2014-
    • Experimental Neurology, 2012-


  • Society for Neuroscience
  • American Epilepsy Society
  • American Neurological Association
  • American Academy of Neurology
  • American Academy for the Advancement of Science
  • Child Neurology Society
  • Endocrine Society
  • International Society of Neuroendocrinology

Faculty Profile: