The ultimate goal of the Jafari Research Group is to add healthy years to human life!


Healthspan Pharmacology

Slowing the aging process delays the progression of age-related diseases such as cancer, Alzheimer’s, and heart disease. The ultimate goal of our work is to improve healthspan and add healthy years to human life.

Drosophila melanogaster

Over the past 10 years, using fruit flies as as our model system, we have developed an algorithm and a number of bioassays to identify compounds that increased lifespan as well as improve healthspan.

Botanical Extracts

While some studies have shown that plants and botanical extracts such as Rhodiola rosea and Rosa demascena may impact age-related diseases, there are large gaps in the human knowledge about the mechanisms through which these natural products modulate aging. Our research hopes to bridge that gap in knowledge.

Recent Publications

January 2016
The impact of green tea polyphenols on development and reproduction in Drosophila melanogaster
December 2014
Extension of Drosophila lifespan by cinnamon through a sex-specific dependence on the insulin receptor substrate chico. Experimental Gerontology
July 2014
Green Tea Polyphenols Extend the Lifespan of Male Drosophila melanogaster While Impairing Reproductive Fitness
May 2013
Extension of Drosophila lifespan by Rhodiola rosea through a mechanism independent from dietary restriction



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