Publications

Ledray, A.P.; Krest, C.M.; Yosca, T.H.;Mittra, K.M. Ascorbate Peroxidase Compound II Is an Iron(IV) Oxo Species. Journal of the American Chemical Society, 2020, 142, 48, 20419-20425.

Rittle, J.; Field, M.J.; Green, M.T.; Tezcan, A. An efficient, step-economical strategy for the design of functional metalloproteins. Nat. Chem. 11, 434–441 (2019). https://doi.org/10.1038/s41557-019-0218-9

Mittra, K.; Green, M.T. “Reduction Potentials of P450 Compounds I and II: Insight into the Thermodynamics of C-H Bond Activation”, Journal of the American Chemical Society, 2019, 141, 5504-5510.

Onderko, E.O.; Silakov, A.; Yosca, T.H.; Green, M.T. “Characterization of a selenocysteine-ligated P450 compound I reveals direct link between electron donation and reactivity”, Nature Chemistry, 2017, 9, 623-628.

Yosca, T.H.; Ledray, A.P.; Ngo, J.; Green, M.T. “A New Look at the Role of Thiolate Ligation in Cytochrome P450”, Journal of Biological Inorganic Chemistry, 2017, 22, 209-220.

Yosca, T.H.; Langston, M.C.; Krest, C.M.; Onderko, E.L.; Grove, T.L.; Livada, J.; Green, M.T. “Spectroscopic investigations of catalase compound II: Characterization of an iron(IV)hydroxide intermediate in a non-thiolate-ligated heme enzyme”, Journal of the American Chemical Society, 2016, 138, 16016-16023.

Hill, E.A.; Weitz, A.C.; Onderko, E.L.; Romero-Rivera, A.; Guo, Y.; Swart, M.; Bominaar, E.L.; Green, M.T.; Hendrich, M.P.; Lacy, D.C.; Borovik, A.S. “Reactivity of an Fe^IV–Oxo Complex with Protons and Oxidants”, Journal of the American Chemical Society, 2016, 138, 13143-13146.

Yosca, T.H.; Green, M.T. “Preparation of Compound I in P450cam: The Prototypical P450”, Israel Journal of Chemistry, 2016, 56, 834-840.

Krest, C.M.; Silakov, A.; Rittle, J.; Yosca, T.H.; Onderko, E.L.; Calixto, J.C.; Green, M.T. “Significantly Shorter Fe–S Bond in Cytochrome P450-I Is Consistent with Greater Reactivity Relative to Chloroperoxidase”, Nature Chemistry, 2015, 7, 696−702.

Martinie, R.J.; Livada, J.; Chang, W.C.; Green, M.T.; Krebs, C.; Bollinger, J.M.; Silakov, A. “Experimental Correlation of Substrate Position with Reaction Outcome in the Aliphatic Halogenase, SyrB2”, Journal of the American Chemical Society, 2015, 137, 6912−6919.

Neu, H.M.; Yang, T.; Baglia, R.A.; Yosca, T.H.; Green, M.T.; Quesne, M.G., de Visser, S.P.; Goldberg, D.P. “Oxygen-Atom Transfer Reactivity of Axially Ligated Mn(V)–Oxo Complexes: Evidence for Enhanced Electrophilic and Nucleophilic Pathways”, Journal of the American Chemical Society, 2014, 136, 13845−13852.

Yosca, T.H.; Behan, R.K.; Krest, C.M.; Onderko, E.L.; Langston, M.L.; Green, M.T. “Setting an Upper Limit on the Myoglobin Iron(IV)Hydroxide pKa: Insight into Axial Ligand Tuning in Heme Protein Catalysis”, Journal of the American Chemical Society, 2014, 136, 9124−9131.

Silakov, A.; Grove, T.L; Radle, M.I.; Bauerle, M.R.; Green, M.T.; Rosenzweig, A.C. Boal, A.K.; Booker, S.J. “Characterization of a Cross-Linked Protein Nucleic Acid Substrate Radical in the Reaction Catalyzed by RlmN”, Journal of the American Chemical Society, 2014, 136, 8221-8228.

Yosca, T.H.; Rittle, J.; Krest, C.M.; Onderko, E.L.; Silakov, A.; Calixto, J.C.; Behan, R.K.; Green, M.T. “Iron(IV)hydroxide pKa and the Role of Thiolate Ligation in C-H Bond Activation by Cytochrome P450”, Science, 2013, 342, 825-829.

Dassama, L.M.K.; Silakov, A.; Krest, CM.; Calixto, J.C; Krebs, C.;  Bollinger, J.M. Jr.; and Green, M.T. “A 2.8 Å Fe-Fe Separation in the Fe₂^III/IV Intermediate (X) from Escherichia coli Ribonucleotide Reductase”, Journal of the American Chemical Society, 2013, 135, 16758-16761.

Krest, C.M.; Onderko, E.L.; Yosca, T.H.; Calixto, J.C.; Karp, R.F.; Livada, J.; Rittle, J.; and Green, M.T. “Reactive Intermediates in Cytochrome P450 Catalysis”, Journal of Biological Chemistry, 2013, 288, 17074-17081.

Grove, T.L.; Livada, J.; Green, M.T.; Booker, S.J.; Silakov, A., “A Substrate Radical in Catalysis by the Antibiotic Resistance Protein Cfr”, Nature Chemical Biology, 2013, 9, 422-427.

Dassama, L.M.K.; Yosca, T.H.; Conner, D.; Lee, M.H.; Blanc, B.; Streit, B.R.; Green, M.T.; DuBois, J.L.; Krebs, C.; Bollinger, J.M. Jr. “O2-Evolving Chlorite Dismutase as a Tool for Studying O2-Utilizing Enzymes”, Biochemistry, 2012, 51, 1607–1616.

Rittle, J.; Green, M.T. “Cytochrome P450 Compound I: Capture, Characterization, and C-H Bond Activation Kinetics”, Science, 2010, 330, 933-937.

Stasser, J.; Namuswe, F.; Kasper, G.D.; Jiang, Y.B.; Krest, C.M.; Green, M.T.; Penner-Hahn J.; Goldberg, D.P. “X-ray Absorption Spectroscopy and Reactivity of Thiolate-Ligated Fe-III-OOR Complexes”, Inorganic Chemistry, 2010, 49, 9178-9190.

Ye, S.; Hoffart, L.M.; Price, J.C.; Barr, E.W.; Green, M.T.; Bollinger, J.M.; Krebs, C.; Neese, F. “Cryoreduction of the NO-adduct of Taurine:α-Ketoglutarate Dioxygenase (TauD) Yields an Elusive {FeNO}⁸ Species” Journal of the American Chemical Society, 2010, 132, 4739-4751.

Rittle, J.; Green, M.T. “Cytochrome P450: The Active Oxidant and Its Spectrum”, Inorganic Chemistry, 2010, 49, 3610-3617.

Matthews, M.L.; Krest, C.M.; Barr, E.W.; Vaillancourt, F.H.; Walsh, C.T.; Green, M.T.; Krebs, C.; Bollinger, J.M., Jr.  “Substrate-Triggered Formation and Remarkable Stability of the C-H-Cleaving Chloroferryl Intermediate in the Aliphatic Halogenase, SyrB2”, Biochemistry, 2009, 48, 4331-4343.

Green, M.T. “C-H bond activation in heme proteins: the role of thiolate ligation in cytochrome P450”, Curr. Opin. Chem. Biol., 2009, 13, 84-88.

Bollinger, J. M., Jr.; Jiang, W.; Green, M. T.; Krebs, C. “The Manganese(IV)/Iron(III) Cofactor of Chlamydia trachomatis Ribonucleotide Reductase: Structure, Assembly, Radical Initiation, and Evolution” Curr. Opin. Struct. Biol., 2008, 18, 650-657.

Namuswe, F.; Kasper, G.D.; Narducci Sarjeant, A.A.; Hayashi T.; Krest, C.M.; Green, M.T.; Moenne-Loccoz, P.; Goldberg, D.P. “Rational Tuning of the Thiolate Donor in Model Complexes of Superoxide Reductase: Direct Evidence for a trans Influence in Fe^III – OOR Complexes”, Journal of the American Chemical Society, 2008, 130, 14189-14200.

Younker, J.M.; Krest, C.M.; Jiang, W.; Krebs, C.; Bollinger, J.M., Jr.; Green, M.T. ^“Structural Analysis of the Mn^IV/Fe^III Cofactor of Chlamydia trachomatis Ribonucleotide Reductase by Extended X-ray Absorption Fine Structure Spectroscopy and Density Functional Theory Calculations”, Journal of the American Chemical Society, 2008, 130, 15022-15027.

Behan R.K.; Hoffart, L.M.; Stone, K.L.; Krebs, C.; Green, M.T. “Reaction of Cytochrome P450 with Peroxynitrite Yields Nitrosyl Complex”, Journal of the American Chemical Society, 2007, 129, 5855-5859.

Hendrich, M.T., Gunderson, W., Mehn, M.P., Betley, T.A., Lu, C.C., Behan, R.K., Green, M.T., Peters, J.C., “On the Feasibility of N2 Fixation via a Single Site Fe(I)/Fe(IV) Cycle – Spectroscopic Studies of Fe(I)-N2-Fe(I), Fe(IV)ºN, and Related Species”, Proceedings of the National Academy of Sciences, 2006, 103, 17107-17112.

Behan R.K.; Hoffart, L.M.; Stone, K.L.; Krebs, C.; Green, M.T. “Evidence for Basic Ferryls in Cytochrome P450”, Journal of the American Chemical Society, 2006, 128, 11471-11474.

Stone, K.L.; Behan R.K.; Green, M.T. “Resonance Raman Spectroscopy of Chloroperoxidase Compound II Provides Direct Evidence for the Existence of an Iron(IV)-Hydroxide”, Proceedings of the National Academy of Sciences, 2006, 103, 12307-12310.

Parsell, T.H.; Behan, R.K.; Green, M.T.; Hendrich, M.P.; Borovik, A.S.  “Preparation and Properties of a Monomeric Mn^IV-Oxo Complex”, Journal of the American Chemical Society, 2006, 128, 8728-8729.

Stone, K.L.; Hoffart, L.M.; Behan R.K.; Krebs, C.; Green, M.T. “Evidence for Two Ferryl Species in Chloroperoxidase Compound II”, Journal of the American Chemical Society, 2006, 128, 6147-6153.

Behan, R.K.; Green, M.T. “On the Status of Ferryl Protonation”, Journal of Inorganic Biochemistry, 2006, 100, 448-459.

Green, M.T. “Application of Badger’s Rule to Heme and Non-Heme Iron-Oxygen Bonds: An Examination of Ferryl Protonation States”, Journal of the American Chemical Society, 2006, 128, 1902-1906.

Stone, K.L.; Behan, R.K.; Green, M.T. “X-Ray Absorption Spectroscopy of Chloroperoxidase Compound I: Insight into the Reactive Intermediate of P450 Chemistry”, Proceedings of the National Academy of Sciences, 2005, 102, 16563-16565.

Krebs, C.; Price, J.C.; Baldwin, J.; Saleh, S.; Green, M.T.; Bollinger, J.M., Jr. “Rapid Freeze-Quench ⁵⁷Fe-Mössbauer Spectroscopy: Monitoring Changes of an Iron-Containing Active Site during a Biochemical Reaction”, Inorganic Chemistry, 2005, 44, 742-757.

_­­Green, M.T.; Dawson, J.H.; Gray, H.B., “Oxoiron(IV) in Chloroperoxidase Compound II is Basic: Implications for P450 Chemistry”, Science 2004, 304, 1653-1656.

Miller, J.E.; Di Bilio, A.J.; Wehbi, W.A.; Green, M.T.; Winkler, J.R.; Gray, H.B., “Electron Tunneling in Rhenium-Modified Pseudomonas aeruginosa Azurins”, Biochimica Biophysica Acta – Bioenergetics, 2004, 1655, 59-63.

Dmochowski, I.J.; Dunn, A.R.; Wilker, J.J.; Crane, B.R.; Green, M.T.; Dawson, J.H.; Sligar, S.G; Winkler, J.R.; Gray, H.B. “Ruthenium Probes of P450 Structure and Mechanism”, Methods in Enzymology, 2002, 357, 120-133.

Green, M.T. “The Structure and Spin Coupling of Catalase Compound I: A Study of Non-Covalent Effects”, Journal of the American Chemical Society, 2001, 123, 9218-9219.

Southern, J.S.; Green M.T.; Hattan, P.M.; Hillhouse, G.L.; Guzei, I.A.; Rheingold, A.L. “Reagent-Specific Protonations of trans-Re(CO)2(NO)(PPH3)2 That Give the Neutral Nitroxyl Complex cis,trans-Re(Cl)(CO)2(NH=O)(PPH3)2 or the Cationic Hydride Complex [trans,trans-Re(H)(CO)2(NO)(PPH3)2+]-[SO3CF3-]”, Inorganic Chemistry, 2001, 40, 6039-6046.

Green, M.T. “Imidazole Ligated Compound I Intermediates: The Effects of Hydrogen Bonding”, Journal of the American Chemical Society, 2000, 122, 9495-9499.

Frank, N.L.; Clerac, R.; Sutter, J.P.; Daro, N.; Kahn, O.; Coulon, C.; Green, M.T.; Golhen, S.; Ouahab, L. “Synthesis, Crystal Structure, Magnetic, and Electron Paramagnetic Resonance Properties of a Spiroconjugated Biradical. Evidence for Spiroconjugation Exchange Pathway”, Journal of the American Chemical Society, 2000, 122, 2053-2061.

Green, M.T. “Evidence for Sulfur-Based Radicals in Thiolate Compound I Intermediates”, Journal of the American Chemical Society, 1999, 121, 7939-7924.

Kozmin, S.; Green, M.T.; Rawal, V. “An Experimental and Theoretical Study of the Kinetics of Diels-Alder Reaction with Aminosiloxydiene”, Journal of Organic Chemistry, 1999, 64, 8045-8047.

Green, M.T.; McCormick, T.A. “Controlling the Singlet-Triplet Splitting in Metal Complexes of Bis(verdazyl) Diradicals: A Step Towards Magnetic Polymers”, Inorganic Chemistry, 1999, 38, 3061-3065.

Green, M.T. “Role of the Axial Ligand in Determining the Spin State of Resting Cytochrome P450”, Journal of the American Chemical Society, 1998, 120, 10772-10773.

Green, M.T.; Robert, V.; Burdett, J.K. “The Temperature-Dependence of Charge Carrier Concentrations in Low-Dimensional Metals: A Breathing Band Gap Model”, Journal of Physical Chemistry B, 1997, 101, 10290-10294.

Peiris, S.M.; Green, M.T.; Heinz, D.L.; Burdett, J.K. “Experimental and Theoretical Studies of ScS under Pressure”, Inorganic Chemistry, 1996, 35, 6933-6936.

Green, M.T.; Hughbanks, T. “The Electronic Structure of Nitridometallates; Molecular and Extended Chain Ions”, Inorganic Chemistry, 1993, 32, 5611-5615.