Human species’ use of plants as medicines dates back to Paleolithic times. There remain many botanical medicine secrets still to unlock, but we are now against the clock, as our exploitation of the planet reduces biodiversity and with it the natural apothecary upon which we have relied for so long. Read article…
Congratulations to Rian Manville and Derk Hogenkamp for their paper out today in Communications Biology reporting the unexpected ability of rosemary and its constituent carnosic acid to selectively open KCNQ potassium channel isoforms in the brain. The finding may give clues to the centuries-old use of rosemary as a memory aid and for other neurological…
Congratulations to Rian Manville for another first-author paper in Nature Communications! Our work, in conjunction with Valley Childrens’ Hospital Pediatrician Rich Sidlow, and J. Alfredo Freites and Doug Tobias in UCI Dept of Chemistry, describes the molecular mechanism of action of Kwakwaka’wakw First Nations botanical ataxia therapies down to the atomic level, and shows that…
Multiple news sites covered the recent paper by Rian Manville and colleagues published in Nature Communications showing that Kwakwaka’wakwa botanical ataxia therapies rescue function of Kv1.1 channels carrying Episodic Ataxia Type 1 mutations….