At temperatures reaching 112F, we had to work for our plants on this collection trip!…
Abbott Bioelectricity Lab Medicinal Plant Collection Trip 033 – Boyd Deep Canyon, Indian Wells, CA
Abbott lab celebrates recent ataxia paper publication – Fogo de Chao, Irvine
Lively conversation all around!…
Abbott lab blog post about our rosemary discovery
Human species’ use of plants as medicines dates back to Paleolithic times. There remain many botanical medicine secrets still to unlock, but we are now against the clock, as our exploitation of the planet reduces biodiversity and with it the natural apothecary upon which we have relied for so long. Read article…
A unique potassium channel opener from rosemary!
Congratulations to Rian Manville and Derk Hogenkamp for their paper out today in Communications Biology reporting the unexpected ability of rosemary and its constituent carnosic acid to selectively open KCNQ potassium channel isoforms in the brain. The finding may give clues to the centuries-old use of rosemary as a memory aid and for other neurological…
New paper from the Abbott and Tobias labs on Native American botanical medicines for ataxia
Congratulations to Rian Manville for another first-author paper in Nature Communications! Our work, in conjunction with Valley Childrens’ Hospital Pediatrician Rich Sidlow, and J. Alfredo Freites and Doug Tobias in UCI Dept of Chemistry, describes the molecular mechanism of action of Kwakwaka’wakw First Nations botanical ataxia therapies down to the atomic level, and shows that…
Abbott Bioelectricity Lab in the news
Multiple news sites covered the recent paper by Rian Manville and colleagues published in Nature Communications showing that Kwakwaka’wakwa botanical ataxia therapies rescue function of Kv1.1 channels carrying Episodic Ataxia Type 1 mutations….
New paper out from the Hu and Abbott labs shows that aloperine prevents sudden cardiac death
The paper, published in FASEB Journal, uses a rat model of ischemia/reperfusion (IR) injury to study the antiarrhythmic effects of aloperine, an alkaloid from Sophora sp. used in traditional medicine in China. Aloperine was found to be 100% effective at preventing IR injury-induced sudden cardiac death….
Discussing herbal medicine at the Susan Samueli Integrative Health Institute Women’s Wellness Day
Geoff Abbott talks about Rian Manville’s discovery that E-2-dodecenal from cilantro activates neuronal KCNQ2/3 channels, explaining folk medicine use of cilantro and culantro as anticonvulsants….