Sonia Chinedu, Bio199 Undergraduate Researcher in the Abbott Bioelectricity Lab, presents her research at the School of Medicine Excellence in Research poster session, 4/18/2022. Her work, under the guidance of Dr. Ryan Yoshimura in the Abbott Bioelectricity Lab, focuses on discovery of the molecular mechanisms of Native American folk medicine analgesics….
March 26, 2022, Solstice, Cheeseboro and Palo Comado Canyons, Santa Monica Mountains National Recreation Area….
Boyd Deep Canyon, Indian Wells, CA, March 4, 2022. The Philip L. Boyd Deep Canyon Research Center is a field station of the University of California, Riverside and the Natural Reserve System….
Cima, Kelbaker, Zzyzx, Mojave National Preserve, February 18, 2022…
In two reports published this fall in collaboration with the laboratory of former Abbott lab post-doc Dr. Zhaoyang Hu, it is shown that the SGLT2 inhibitor empagliflozin protects the heart against sudden cardiac death, and the lungs against ischemia/reperfusion injury, even in nondiabetic animal models. These findings potentially broaden the clinical indications for empagliflozin. EmpagliflozinProtects…
Mojave National Preserve, CA, December 2021….
In collaboration with the Giraldez and de la Rosa labs at Universidad de La Laguna, Tenerife, we help to uncover the ability of SGK1.1, the neuronal isoform of the serum and glucocorticoids-regulated kinase 1, to increase activity of KCNQ2/3 loss-of-function mutants, providing another potential molecular target for pharmacological rescue of neuronal M-current. Activation of SGK1.1…
11.11.21. In time for Native American Heritage Month, Abbott Bioelectricity Lab has a paper published today in Frontiers in Physiology reporting the molecular mechanistic rationale underlying dual use by Native Americans of specific plants as both analgesics and gastrointestinal aids. The project was a collaboration with the National Park Service and specifically the Redwood Creek…
Zuma Canyon, Malibu, CA…
