2022
Weghorst F, Mirzakhanyan Y, Hernandez K, Gershon PD, and Cramer KS (2022). Non-apoptotic caspase activity preferentially targets a novel consensus sequence associated with cytoskeletal proteins in the developing auditory brainstem. Front. Cell and Dev. Neurosci. 10: 844844. doi: 10.3389/fcell.2022.844844. Download PDF
Chokr S, Milinkeviciute G, and Cramer KS (2022). Synapse maturation and developmental impairment in the medial nucleus of the trapezoid body. Front. Integr. Neurosci. 10: 804221. doi: 10.3389/fnint.2022.804221. Download PDF
2021
Milinkeviciute G, Chokr S, Castro E, and Cramer KS (2021). CX3CR1 mutation alters synaptic and astrocytic protein expression, topographic gradients, and response latencies in the auditory brainstem. J. Comp. Neurol. 529(11):3076-3097. doi: 10.1002/cne.25150. Download PDF
2020
Weghorst F, Mirzakhanyan Y, Samimi K, Dhillon M, Barzik M, Cunningham LL, Gershon PD, and Cramer KS (2020). Caspase-3 cleaves extracellular vesicle proteins during auditory brainstem development. Front. Cell. Neurosci. 14: 573345. doi: 10.3389/fncel.2020.573345. Download PDF
Milinkeviciute G, Chokr S, and Cramer KS (2020). Auditory brainstem deficits from early treatment with a CSF1R inhibitor largely recover with microglial repopulation. eNeuro 8 (2). doi:
2019
Milinkeviute G, Henningfield CM, Muniak MA, Chokr SM, Green KN, and Cramer KS (2019). Microglia regulate pruning of specialized synapses in the auditory brainstem. Front. Neural Circuits 13:55. Doi: 10.3389/fncir.2019.00055 Download PDF
Weghorst F and Cramer KS (2019) The evolution of hearing and balance. Elife. 2019 Feb 8;8. pii: e44567. doi: 10.7554/eLife.44567. Download PDF
2018
Milinkeviciute G and Cramer KS. (2018) Glial cells in the auditory brainstem. In K. Kandler (ed), Neuroscience Handbook Series: The Auditory Brainstem: Organization, Function, and Plasticity. Oxford University Press. Download PDF
2017
Rotschafer SE, Cramer KS (2017) Developmental emergence of phenotypes in the auditory brainstem nuclei of Fmr1 knockout mice. eNeuro. ENEURO.0264-17.2017. doi: 10.1523/ENEURO.0264-17.2017. eCollection 2017 Nov-Dec. Download PDF
2016
Rotschafer SE, Allen-Sharpley MR and Cramer KS (2016) Axonal Cleaved Caspase-3 Regulates Axon Targeting and Morphogenesis in the Developing Auditory Brainstem. Front. Neural Circuits 10:84. doi: 10.3389/fncir.2016.00084 Download PDF
Cramer KS and Rubel EW (2016) Glial cell contributions to auditory brainstem development. Front. Neural Circuits. 10:83. doi: 10.3389/fncir.2016.00083 Download PDF
Cramer KS and Miko IJ (2016) Eph-ephrin signaling in nervous system development. F1000Research 2016, 5(F1000 Faculty Rev):413 (doi: 10.12688/f1000research.7417.1) Download PDF
2015
Abdul-Latif ML, Salazar JA, Marshak S, Dinh ML, Cramer KS (2015). Ephrin-A2 and ephrin-A5 guide contralateral targeting but not topographic mapping of ventral cochlear nucleus axons. Neural Dev. 2015 Dec 15;10:27. doi: 10.1186/s13064-015-0054-6. Download PDF
Rotschafer SE, Marshak S, and Cramer KS (2015). Deletion of Fmr1 alters function and synaptic inputs in the auditory brainstem. PLoS One, 13;10(2):e0117266. doi: 10.1371/journal.pone.0117266. Download PDF
2014
Dinh ML, Koppel SJ, Korn MJ, and Cramer KS. (2014) Distribution of glial cells in the auditory brainstem: Normal development and effects of unilateral lesion. Neuroscience (278C): 237-252. Download PDF
Cramer KS and Gabriele ML. (2014) Axon guidance in the auditory system: Multiple functions of Eph receptors. Neuroscience (277C): 152-162. Download PDF
2013
Allen-Sharpley MR, Tjia M, and Cramer KS. (2013) Differential roles for EphA and EphB signaling in segregation and patterning of central vestibulocochlear nerve projections. PLoS One, Oct 10;8(10):e78658. doi: 10.1371/journal.pone.0078658. Download PDF
Allen-Sharpley MR, Tjia M, and Cramer KS. (2013) Selective tracing of auditory fibers in the avian embryonic vestibulocochlear nerve. J. Vis. Exp. (73), e50305, doi:10.3791/50305. Download PDF
Nakamura PA and Cramer KS. (2013) EphB2 signaling regulates lesion-induced axon sprouting but not critical period length in the postnatal auditory brainstem. Neural Dev. Feb 5;8:2. doi: 10.1186/1749-8104-8-2. Download PDF
2012
Allen-Sharpley MR and Cramer KS. (2012) Coordinated Eph-ephrin signaling guides migration and axon targeting in the avian auditory system. Neural Dev. 7:29. doi: 10.1186/1749-8104-7-29. Download PDF
Korn MJ, Koppel SJ, Li LH, Mehta D, Mehta SB, Seidl AH, and Cramer KS. (2012). Astrocyte-secreted factors modulate the developmental distribution of inhibitory synapses in nucleus laminaris of the avian auditory brainstem. J. Comp. Neurol. 520:1262-1277. Download PDF
2011
Intskirveli I, Metherate R, and Cramer KS. (2011) Null mutations in EphB receptors decrease sharpness of frequency tuning in primary auditory cortex. PLoS One 6: e26192. Download PDF
Korn MJ, Koppel SJ, and Cramer KS. (2011) Astrocyte secreted factors modulate a gradient of primary dendritic arbors in nucleus laminaris of the avian auditory brainstem. PLoS One 6:e27383. Download PDF
Nakamura PA and Cramer KS. (2011) Formation and maturation of the calyx of Held. Hearing Research 276:70-78. Download PDF
2010
Hsieh CY, Nakamura PA, Luks SO, Miko IJ, Henkemeyer M, and Cramer KS. (2010) Ephrin-B reverse signaling is required for formation of strictly contralateral auditory brainstem pathways. J. Neurosci. 30:9840-9849. Download PDF
2008
Korn, MJ and Cramer KS. (2008) The distribution of glial associated proteins in the developing chick auditory brainstem. Developmental Neurobiology 68:1093-1106. Download PDF
Miko IJ, Henkemeyer M, and Cramer KS. (2008) Auditory brainstem responses are impaired in EphA4 and ephrin-B2 deficient mice. Hearing Research 235:39-46. Download PDF
2007
Korn MJ and Cramer KS. (2007) Windowing chicken eggs for developmental studies. J Vis Exp. (8) 306. Download PDF
Korn MJ and Cramer KS. (2007) Placing growth factor-coated beads on early stage chicken embryos. J Vis Exp. (8) 307. Download PDF
Miko IJ, Nakamura PA, Henkemeyer M, and Cramer KS. (2007) Auditory brainstem neural activation patterns are altered in EphA4 and ephrin-B2 deficient mice. J. Comp. Neurol. 505: 669-681. Download PDF
Hsieh CY, Hong CT, and Cramer KS. (2007) Deletion of EphA4 enhances deafferentation-induced ipsilateral sprouting in auditory brainstem projections. J. Comp. Neurol. 504: 508-518. Download PDF
Huffman KJ and Cramer KS. (2007) EphA4 misexpression alters tonotopic projections in the auditory brainstem. Developmental Neurobiology 67: 1655-1668. Download PDF
2006
Hsieh CY and Cramer KS. (2006) Deafferentation induces novel axonal projections in the auditory brainstem after hearing onset. J. Comp. Neurol. 497: 589-599. Download PDF
Cramer KS, Cerretti DP, and Siddiqui SA. (2006) EphB2 regulates axonal growth at the midline in the developing auditory brainstem. Developmental Biology 295: 76-89. Download PDF
2005
Cramer KS. (2005) Eph proteins and the assembly of auditory circuits. Hearing Research 206: 42-51. Download PDF
Siddiqui SA and Cramer KS. (2005) Differential expression of Eph receptors and ephrins in the cochlear ganglion and eighth cranial nerve of the chick embryo. J. Comp. Neurol. 482: 309-319. Download PDF
Burger RM, Cramer KS, Pfeiffer JD, and Rubel EW. (2005) The avian superior olivary nucleus provides divergent inhibitory input to parallel auditory pathways. J. Comp. Neurol. 481: 6-18. Download PDF
2004
Person AL, Cerretti DP, Pasquale EB, Rubel EW, and Cramer KS. (2004) Tonotopic gradients of Eph family proteins in the chick nucleus laminaris during synaptogenesis. J. Neurobiol. 60: 28-39. Download PDF
Cramer KS, Bermingham-McDonogh OM, Krull CE, and Rubel EW. (2004) EphA4 signaling promotes axon segregation in the developing auditory system. Developmental Biology 269: 26-35. Download PDF
Eberhart J, Barr J, O’Connell S, Flagg A, Swartz ME, Cramer KS, Tosney, K, Pasquale EB, and Krull CE. (2004) Ephrin-A5 exerts positive or inhibitory effects on distinct subsets of EphA4-positive motor neurons. J. Neurosci. 24: 1070-1078. Download PDF
2002
Rubel EW and Cramer KS. (2002) Choosing axonal real estate: location, location, location. Commentary, J. Comp. Neurol. 448: 1-5. Download PDF
Cramer KS, Karam SD, Cerretti DP, Pasquale EP, and Rubel EW. (2002) Expression of EphB receptors and ephrin-B ligands in the developing chick auditory brainstem. J. Comp. Neurol. 452: 51-64. Download PDF
2000
Cramer KS, Rosenberger MH, Frost DM, Cochran SL, Pasquale EB, and Rubel EW. (2000) Developmental regulation of EphA4 expression in the chick auditory brainstem. J. Comp. Neurol. 426: 270-278. Download PDF
Cramer KS, Fraser SE, and Rubel EW. (2000) Embryonic origins of auditory brainstem nuclei in the chick hindbrain. Developmental Biology 224: 138-151. Download PDF
1994 – 1999
Hahm J, Cramer KS and Sur M (1999) Pattern formation by retinal afferents in the ferret lateral geniculate nucleus: Developmental segregation and the role of N-methyl-D-aspartate receptors. J. Comp. Neurol. 411: 327-345.
Cramer KS and Sur M. (1999) The neuronal form of nitric oxide synthase is required for sublaminar segregation in the ferret lateral geniculate nucleus. Dev. Brain Res. 116: 79-86.
Leamey CA, Cramer KS and Sur M (1998) The role of activity-dependent mechanisms in pattern formation in the retinogeniculate pathway. In Development and Organization of the Retina: From Molecules to Function, eds. L. Chalupa and B. Finlay, pp. 309-318.
Cramer KS, Leamy CA and Sur M (1998) Nitric oxide: a signaling molecule in visual system development. Progress in Brain Research 118: 101-114.
Cramer KS and Sur M (1997) Blockade of afferent impulse activity disrupts ON/OFF sublamination in the ferret lateral geniculate nucleus. Dev. Brain Res. 98: 287-290.
Angelucci A, Bricolo E, Clasca F, Cramer KS, and Sur M (1997) Experimentally induced retinal projections to the ferret auditory thalamus: Development of clustered eye-specific patterns in a novel target. J. Neurosci. 17: 2040-2055.
Cramer KS, Angelucci A, Hahm J, Bogdanov MB, and Sur M (1996) A role for nitric oxide in the development of the ferret retinogeniculate projection. J. Neurosci. 16: 7995-8004.
Cramer KS and Sur M (1996) The role of NMDA receptors and nitric oxide in retinogeniculate development. Progress in Brain Research 108: 235-244.
Cramer KS and Sur M (1995) Activity-dependent remodeling of connections in the mammalian visual system. Current Opinion in Neurobiology 5: 106-111.
Cramer KS, Moore CI and Sur M (1995) Transient expression of NADPH-diaphorase in the lateral geniculate nucleus of the ferret during early postnatal development. J. Comp. Neurol. 353: 306-316.
Cramer KS and Van Essen DC (1995) Lack of topography in the spinal cord projection to the rabbit soleus muscle. J. Comp. Neurol. 351: 404-414.
Cramer KS and Van Essen DC (1995) Maturation of fast and slow motor units during synapse elimination in the rabbit soleus muscle. Developmental Biology 171: 16-26.