PubMed Search | Google Scholar
2023
Meli, Vijaykumar S., Praveen Krishna Veerasubramanian, Timothy L. Downing, Wenqi Wang, and Wendy F. Liu. “Mechanosensation to inflammation: Roles for YAP/TAZ in innate immune cells.” Science Signaling 16, no. 783 (2023): eadc9656.
Urban, Lauren A., Jiachun Li, Gokhan Gundogdu, Annie Trinh, Hanjuan Shao, Travis Nguyen, Joshua R. Mauney, and Timothy L. Downing. “DNA Methylation Dynamics During Esophageal Epithelial Regeneration Following Repair with Acellular Silk Fibroin Grafts in Rat.” Advanced Biology 7, no. 5 (2023): 2200160.
2022
Ren, Honglei, Robert B. Taylor, Timothy L. Downing, and Elizabeth L. Read. “Locally correlated kinetics of post-replication DNA methylation reveals processivity and region specificity in DNA methylation maintenance.” Journal of the Royal Society Interface 19, no. 195 (2022): 20220415.
Veerasubramanian, Praveen Krishna, Victor C. Joe, Wendy F. Liu, and Timothy L. Downing. “Characterization of Macrophage and Cytokine Interactions with Biomaterials Used in Negative-Pressure Wound Therapy.” Bioengineering 9, no. 1 (2022): 2.
2021
Veerasubramanian, Praveen Krishna, Hanjuan Shao, Vijaykumar S. Meli, Tri Andrew Q. Phan, Thuy U. Luu, Wendy F. Liu, and Timothy L. Downing. “A Src-H3 acetylation signaling axis integrates macrophage mechanosensation with inflammatory response.” Biomaterials 279 (2021): 121236.
Downing, Timothy L. “Towards spheroid-omics.” Nature Methods 18, no. 11 (2021): 1283-1285.
Chinn, Carlene A., Honglei Ren, Julien LP Morival, Qing Nie, Marcelo A. Wood, and Timothy L. Downing. “Examining age-dependent DNA methylation patterns and gene expression in the male and female mouse hippocampus.” Neurobiology of aging 108 (2021): 223-235.
Morival, Julien LP, Halida P. Widyastuti, Cecilia HH Nguyen, Michael V. Zaragoza, and Timothy L. Downing. “DNA methylation analysis reveals epimutation hotspots in patients with dilated cardiomyopathy-associated laminopathies.” Clinical epigenetics 13 (2021): 1-20.
Urban, Lauren A., Annie Trinh, Eric Pearlman, Albert Siryaporn, and Timothy L. Downing. “The impact of age-related hypomethylated DNA on immune signaling upon cellular demise.” Trends in immunology 42, no. 6 (2021): 464-468.
2020
Veerasubramanian, Praveen Krishna, Annie Trinh, Navied Akhtar, Wendy F. Liu, and Timothy L. Downing. “Biophysical and Epigenetic Regulation of Cancer Stemness, Invasiveness, and Immune Action.” Current tissue microenvironment reports 1 (2020): 277-300.
Meli, Vijaykumar S., Hamza Atcha, Praveen Krishna Veerasubramanian, Raji R. Nagalla, Thuy U. Luu, Esther Y. Chen, Christian F. Guerrero-Juarez et al. “YAP-mediated mechanotransduction tunes the macrophage inflammatory response.” Science advances 6, no. 49 (2020): eabb8471.
Busto-Moner, Luis, Julien Morival, Honglei Ren, Arjang Fahim, Zachary Reitz, Timothy L. Downing, and Elizabeth L. Read. “Stochastic modeling reveals kinetic heterogeneity in post-replication DNA methylation.” PLoS computational biology 16, no. 4 (2020): e1007195.
2019
Meli, Vijaykumar S., Praveen K. Veerasubramanian, Hamza Atcha, Zachary Reitz, Timothy L. Downing, and Wendy F. Liu. “Biophysical regulation of macrophages in health and disease.” Journal of leukocyte biology 106, no. 2 (2019): 283-299.
2018
Charlton, Jocelyn, Timothy L. Downing, Zachary D. Smith, Hongcang Gu, Kendell Clement, Ramona Pop, Veronika Akopian et al. “Global delay in nascent strand DNA methylation.” Nature structural & molecular biology 25, no. 4 (2018): 327-332.
2017
Liu, Linan, Shirley X. Zhang, Wenbin Liao, Henry P. Farhoodi, Chi W. Wong, Claire C. Chen, Aude I. Ségaliny et al. “Mechanoresponsive stem cells to target cancer metastases through biophysical cues.” Science Translational Medicine 9, no. 400 (2017): eaan2966.
2013
Downing, Timothy L., Jennifer Soto, Constant Morez, Timothee Houssin, Ashley Fritz, Falei Yuan, Julia Chu, Shyam Patel, David V. Schaffer, and Song Li. “Biophysical regulation of epigenetic state and cell reprogramming.” Nature materials 12, no. 12 (2013): 1154-1162.
Saadai, Payam, Aijun Wang, Yvette S. Nout, Timothy L. Downing, Katrine Lofberg, Michael S. Beattie, Jacqueline C. Bresnahan, Song Li, and Diana L. Farmer. “Human induced pluripotent stem cell-derived neural crest stem cells integrate into the injured spinal cord in the fetal lamb model of myelomeningocele.” Journal of pediatric surgery 48, no. 1 (2013): 158-163.
2012
Downing, Timothy L., Aijun Wang, Zhi-Qiang Yan, Yvette Nout, Andy L. Lee, Michael S. Beattie, Jacqueline C. Bresnahan, Diana L. Farmer, and Song Li. “Drug-eluting microfibrous patches for the local delivery of rolipram in spinal cord repair.” Journal of controlled release 161, no. 3 (2012): 910-917.
2011
Saadai, Payam, Yvette S. Nout, Jose Encinas, Aijun Wang, Timothy L. Downing, Michael S. Beattie, Jacqueline C. Bresnahan, Song Li, and Diana L. Farmer. “Prenatal repair of myelomeningocele with aligned nanofibrous scaffolds—a pilot study in sheep.” Journal of pediatric surgery 46, no. 12 (2011): 2279-2283.