2020 – 2025

2025

339.  “An Autonomous Abiotic Thermal Protectant for Immunoglobulin G (IgG): Reducing the Need for Cold Chain Storage”, Beverly Chou, Rishad Dalal, Kenneth J. Shea, MS Manuscript in Revision (2025)

338. Computational Study of Polyhomologation: Understanding Reactivity with B, Al, and Ga Catalysts, Darien I. Martínez-Valencia, Leonardo I. Lugo-Fuentes, Gerardo González-García, J. Armando Luján-Montelongo, Kenneth J. Shea, José E. Báez, J. Oscar C. Jiménez-Halla, New Journal of Chemistry, 2025 Advance

337. Integrating Synthetic Hydrogel Nanoparticles with Carbon Dots for Selective Detection of Hemoglobin, Y. Li, M. Zhang, L. Li, K. J. Shea, L. Kang, Z. Meng, M. Xue, Sensors and Actuators B: Chemical, 2025, 423, 2401929

336. PSMA‐Targeting Imprinted Nanogels for Prostate Tumor Localization and Imaging , T Zhang, M Berghaus, Y Li, Q Song, MM Stollenwerk, J Persson, KJ Shea, Advanced Healthcare Materials, 2025, 14, 2401929

2024

335. Abiotic Anti-VEGF Nanoparticle, K. J. Shea, H. Koide, Y. Miura, Y. Hoshino, Y. Nishimura, N. Oku, US Patent 11,938,226 (2024)

2023

334. Design of An Anti-HMGB1 Synthetic Antibody for In Vivo Ischemic/Reperfusion Injury Therapy, Hiroyuki Koide, Chiaki Kiyokawa, Anna Okishima, Keiichi Yoshimatsu, Tatsuya Fukuta, Yu Hoshino, Tomohiro Asai, Yuri Nishimura, Yoshiko Miura, Naoto Oku, Kenneth J. Shea, Journal of the American Chemical Society, 2023, 145, 23143-23151

333. Cooling-Induced, Localized Release of Cytotoxic Peptides from Engineered Polymer Nanoparticles in Living Mice for Cancer Therapy
Hiroyuki Koide, Kazuhiro Saito, Keiichi Yoshimatsu, Beverly Chou, Yu Hoshino, Sei Yonezawa, Naoto Oku, Tomohiro Asai, Kenneth J Shea, Journal of Controlled Release, 2023, 355, 745-759

2022

332. Sustainable Xanthophylls-Containing Poly(ε-caprolactone)s: Synthesis, Characterization, and Use in Green Lubricants, Eloy Rodríguez-de-León, Moustapha Bah, José E. Báez, María T. Hernández-Sierra, Karla J. Moreno, Alejandro Núñez-Vilchis, José Bonilla-Cruz, Kenneth J. Shea RSC Advances, 2022, 12, 30851-30859

331. “Responsive hydrogel-based three-dimensional photonic crystal sensor for lactic acid detection.” Qi Li, Yongsheng Li, Min Xue, Kenneth J. Shea, Zihui Meng, Xiao Dong, Analytical and Bioanalytical Chemistry, 2022, https://doi.org/10.1007/s00216-022-04300-3

330. Quantitative Analysis of Structure Color of Photonic Crystal Sensors Based on HSB Color Space” W. Zhang, L. Qiu, K. J. Shea, J. Fan, Y. Liu, W. Zheng, M. Xue, W. Liu, Z. Xu, X. Feng, X. Dong, Y. Qiao, and Z. Meng*, ACS Appl.Mater. Interfaces 2022, 14, 35010–35019.

329. ” A peptide Epitope − Synthetic hydrogel polymer conjugate that mimics insecticidal protein receptors. Application in environmental and biological analysis ” Zihao Wan, Yalu Chen, Senhua Hu, Qiaolian Chen, Yuxin Li, Xiuhua Chen, Yongjun Lin, Wenfeng Tan, Kenneth J. Shea*, Mingming Liu*. Chemical Engineering Journal, 2022, 451, https://doi.org/10.1016/j.cej.2022.138671

328. “Abiotic Synthetic Antibodies to Target a Specific Protein Domain and Inhibit Its Function” Qiaolian Cheng, Xiaoyang Yu, Zhouxuan Xiong, Zihao Wan, Yuxin Li, Weihua Ma, Wenfeng Tan, Mingming Liu,* and Kenneth J. Shea*, ACS Applied Materials & Interfaces, 2022, 14, 19178-19191.

327. “Electrochemical Probing of Steric, Electrostatic and Hydrophobic Interactions of Large Cations in Polymers with Intrinsic Microporosity” Taylor L. Frey, Krista Fruehauf, Kenneth J. Shea, Zuzanna S. Siwy, Journal of the Electrochemical Society, 2022, 169, 020566.

2021

326. “In situ formed thermogelable hydrogel photonic crystals assembled by thermosensitive IPNs.” Xiaoxiao Li, Di Zhao, Kenneth J. Shea, Xueting Li, and Xihua Lu, Mater. Horiz., 2021, 8, 932-938. doi: DOI https://doi.org/10.1039/D0MH01886D.

325. “Synthetic hydrogel nanoparticles for sepsis therapy.” Hiroyuki Koide, Anna Okishima, Yu Hoshino, Yuri Kamon, Keiichi Yoshimatsu, Kazuhiro Saito, Ikumi Yamauchi, Saki Ariizumi, Yuqi Zhou, Tinghui Xiao, Keisuke Goda, Naoto Oku, Tomohiro Asai, and Kenneth J. Shea, Nature Communications, 2021, 12,1-14, https://doi.org/10.1038/s41467-021-25847-2.

324. “Investigating PLGA microparticle swelling behavior reveals an interplay of expansive intermolecular forces.” Crystal E. Rapier, Kenneth J. Shea, Abraham P. Lee, Nature Scientific Reports, 2021, 11, 14512, DOI: doi.org/10.1038/s41598-021-93785-6 2.

323. “Abiotic Mimic of Matrix Metalloproteinase-9 Inhibitor against Advanced Metastatic Cancer.” Tong Zhang, Kamaran Khurshid Dar, Yuan Li, Jing Guo, Weiliang Sun, Kenneth J. Shea, Yongqin Lv, ACS Biomaterials Science & Engineering, 2021, 7, 3190-3200. PMID: 34152745 , DOI: 10.1021/acsbiomaterials.1c00436

322. “A Biomimetic of Endogenous Tissue Inhibitors of Metalloproteinases: Inhibition Mechanism and  Contribution of Composition, Polymer Size, and Shape to the Inhibitory Effect.” Masahiko Nakamoto, Teresa Escalante, José María Gutiérrez, and Kenneth J. Shea, Nano Letters, 2021, 21, 13, 5663-5670. DOI: doi.org/10.1021/acs.nanolett.1c01357

321. “Abiotic Stimuli Responsive Protein Affinity Reagent for IgG.” Shunsuke Onogi, Shih-Hui Lee, Krista R. Fruehauf and Kenneth J. Shea, Biomacromolecules, 2021, 22, 6, 2641–2648. DOI: doi.org/10.1021/acs.biomac.1c00335.

320. “Metal-free Polymer-based Affinity Medium for Selective Purification of His6-tagged Proteins.” Keiichi Yoshimatsu, Krista R. Fruehauf, Quanhong Zhu, Adam Weisman, Jun Fan, Min Xue, John M.Beierle, Paul E. Rose, Jennifer Aral, Linda F. Epstein, Philip Tagari, Les P. Miranda, Kenneth J. Shea, Biomacromolecules, 2021, 22, 4, 1695–1705. PMID: 33783189 , DOI: 10.1021/acs.biomac.1c00119

319. “A biomass based photonic crystal made of “konjac tofu””. Wenxin Zhang, Min Xue, Kenneth J. Shea, Lili Qiu, Zhibin Xu, Jing Fan, Dan Yan, Zihui Meng, Chinese Chemical Letters, 2021, 32, 01, 587-590.

318. “Synthesis of a High Affinity Complementary Peptide-Polymer Nanoparticle (NP) Pair Using Phage Display.” Shih-Hui Lee, Issa Moody, Zhiyang Zeng, Everly B.  Fleischer, Gregory A. Weiss and Kenneth. J. Shea, ACS Applied. Bio Materials. 2021, 4, 2704–2712. DOI: doi.org/10.1021/acsabm.0c01631


317. “Engineered polymer nanoparticles incorporating L-amino acid groups as affinity reagents for Fibrinogen.” Yongyan Zhu, Ruixuan Liu, Dengyu Wu, Qianqian Yu, Kenneth J. Shea, Quanhong Zhu, Journal of Pharmaceutical Analysis, 2021, 11. DOI: doi.org/10.1016/j.jpha.2020.10.004

2020

316. “Detection of lysozyme in body fluid based on two-dimensional colloidal crystal sensor.” Zhe Wang;,Zihui Meng; Min Xue; Herong Zhang; Kenneth J. Shea; Lingling Kang, Microchemical Journal, 2020, 157, 105073, DOI: doi.org/10.1016/j.microc.2020.105073.

315. “An abiotic mimic of endogenous tissue inhibitors of metalloproteinases. Engineering Synthetic Polymer Nanoparticles for use as a Broad-Spectrum Metalloproteinase Inhibitor. Masahiko Nakamoto, Di Zhao, Olivia Rose Benice, Shih-Hui Lee, Kenneth J. Shea, Journal of the American Chemical Society, 2020, 142, 2338−2345. (https://pubs.acs.org/doi/pdf/10.1021/jacs.9b11481)