Mukherjee Labs Preclinical Imaging

Design and Development of Novel Imaging Methods for Early Diagnosis of Diseases

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Diabetes & Obesity

  • Mukherjee, J., Baranwal, A., Schade, K.N.: Classification of therapeutic and experimental drugs for brown adipose tissue activation: Potential treatment strategies for diabetes and obesity. Current Diabetes Reviews, 12: 414-428, 2016.

 

  • Baranwal, A., Mirbolooki, M.R., Mukherjee, J.: Initial assessment of β3-adrenoceptor activated brown adipose tissue in streptozotocin-induced diabetic rodent model using 18F-FDG PET/CT Molecular Imaging, 14: 561-566, 2015.

 

  • Schade, K.N., Baranwal, A., Liang, C., Mirbolooki, M.R., Mukherjee, J.:  Preliminary Evaluation of β3 Adrenoceptor Agonist-Induced 18F-FDG Metabolic Activity in Brown Adipose Tissue of Obese Zucker Rat. Nuclear Medicine & Biology, 42(8):691-694, 2015 (published online April 2015).

 

  • Mirbolooki, M.R., Schade, K.N., Constantinescu, C.C., Pan, M-L., Mukherjee, J.: Enhancement of 18F-fluorodeoxyglucose metabolism in rat brain frontal cortex using a β3 adrenoceptor agonist. Synapse, 69 (2): 96-98, 2015 (published online November 2014).

 

  • Garcia, A., Venugopal, A., Pan, M-L., Mukherjee, J.: Imaging pancreas in healthy and diabetic rodent model using 18F-fallypride PET/CT. Diabetes Technology. & Therapeutics Development., 16(10): 640-643, 2014 (published online May 2014).

 

  • Mirbolooki, M.R., Upadhyay, S.K., Constantinescu, C., Pan, M.L., Mukherjee, J. Adrenergic pathway activation enhances brown adipose tissue metabolism: A 18F-FDG PET/CT study in mice.  Nucl Med Biol., 41:10-16, 2014 (published on line October 2013).

 

  • Selective Kv1.3 channel blocker as therapeutic for obesity and insulin resistance. Upadhyay SK, Eckel-Mahan KL, Mirbolooki MR, Tjong I, Griffey SM, Schmunk G, Koehne A, Halbout B, Iadonato S, Pedersen B, Borrelli E, Wang PH, Mukherjee J, Sassone-Corsi P, Chandy KG. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):E2239-48. doi: 10.1073/pnas.1221206110. Epub 2013 May 31. PMID: 23729813

 

  • Targeting presynaptic norepinephrine transporter in brown adipose tissue: a novel imaging approach and potential treatment for diabetes and obesity. Mirbolooki MR, Constantinescu CC, Pan ML, Mukherjee J. Synapse. 2013 Feb;67(2):79-93. doi: 10.1002/syn.21617. Epub 2012 Nov 8. PMID: 23080264

 

  • Quantitative assessment of brown adipose tissue metabolic activity and volume using 18F-FDG PET/CT and β3-adrenergic receptor activation. Mirbolooki MR, Constantinescu CC, Pan ML, Mukherjee J. EJNMMI Res. 2011 Dec 1;1(1):30. doi: 10.1186/2191-219X-1-30. PMID: 22214183