Publications

Obenaus, A. and Badaut, J., 2018. Noninvasive Imaging Techniques for Brain Edema: From Basic Science to the Clinic. In Brain Edema (pp. 51-69).

Obenaus, A., Ng, M., Orantes, A.M., Kinney-Lang, E., Rashid, F., Hamer, M., DeFazio, R.A., Tang, J., Zhang, J.H. and Pearce, W.J., 2017. Traumatic brain injury results in acute rarefication of the vascular network. Scientific reports, 7(1), p.239.

Salehi, Arjang, John H. Zhang, and Andre Obenaus. “Response of the cerebral vasculature following traumatic brain injury.” Journal of Cerebral Blood Flow & Metabolism (2017): 0271678X17701460.

Affeldt, B.M., Obenaus, A., Chan, J. and Pardo, A.C., 2017. Region specific oligodendrocyte transcription factor expression in a model of neonatal hypoxic injury. International Journal of Developmental Neuroscience.

Salehi, A., Jullienne, A., Baghchechi, M., Hamer, M., Walsworth, M., Donovan, V., Tang, J., Zhang, J.H., Pearce, W.J. and Obenaus, A., 2017. Up-regulation of Wnt/β-catenin expression is accompanied with vascular repair after traumatic brain injury. Journal of Cerebral Blood Flow & Metabolism, p.0271678X17744124.

Kunert, A., Obenaus, M., Lamers, C.H., Blankenstein, T. and Debets, R., 2017. T cell receptors for clinical therapy: in vitro assessment of toxicity risk. Clinical Cancer Research, pp.clincanres-1012.

Zhang, J.H., Obenaus, A., Liebeskind, D.S., Tang, J., Hartman, R. and Pearce, W.J., 2017. Recanalization, reperfusion, and recirculation in stroke. Journal of Cerebral Blood Flow & Metabolism, p.0271678X17732695.

Belayev, L., Mukherjee, P.K., Balaszczuk, V., Calandria, J.M., Obenaus, A., Khoutorova, L., Hong, S.H. and Bazan, N.G., 2017. Neuroprotectin D1 upregulates Iduna expression and provides protection in cellular uncompensated oxidative stress and in experimental ischemic stroke. Cell Death & Differentiation.

Bolton, J.L., Molet, J., Regev, L., Chen, Y., Rismanchi, N., Haddad, E., Yang, D.Z., Obenaus, A. and Baram, T.Z., 2018. Anhedonia Following Early-Life Adversity Involves Aberrant Interaction of Reward and Anxiety Circuits and Is Reversed by Partial Silencing of Amygdala Corticotropin-Releasing Hormone Gene. Biological psychiatry, 83(2), pp.137-147.

Bhattacharjee, S., Jun, B., Belayev, L., Heap, J., Kautzmann, M.A., Obenaus, A., Menghani, H., Marcell, S.J., Khoutorova, L., Yang, R. and Petasis, N.A., 2017. Elovanoids are a novel class of homeostatic lipid mediators that protect neural cell integrity upon injury. Science advances, 3(9), p.e1700735.

Hirt, L., Fukuda, A.M., Ambadipudi, K., Rashid, F., Binder, D., Verkman, A., Ashwal, S., Obenaus, A. and Badaut, J., 2017. Improved long-term outcome after transient cerebral ischemia in aquaporin-4 knockout mice. Journal of Cerebral Blood Flow & Metabolism, 37(1), pp.277-290.

Jullienne, A., Obenaus, A., Ichkova, A., Savona‐Baron, C., Pearce, W.J. and Badaut, J., 2016. Chronic cerebrovascular dysfunction after traumatic brain injury. Journal of neuroscience research, 94(7), pp.609-622.

Bajwa, N.M., Halavi, S., Hamer, M., Semple, B.D., Noble-Haeusslein, L.J., Baghchechi, M., Hiroto, A., Hartman, R.E. and Obenaus, A., 2016. Mild concussion, but not moderate traumatic brain injury, is associated with long-term depression-like phenotype in mice. PloS one, 11(1), p.e0146886.

Yang, P., Manaenko, A., Xu, F., Miao, L., Wang, G., Hu, X., Guo, Z.N., Hu, Q., Hartman, R.E., Pearce, W.J. and Obenaus, A., 2016. Role of PDGF-D and PDGFR-β in neuroinflammation in experimental ICH mice model. Experimental neurology, 283, pp.157-164.

Wu, J., Zhang, Y., Yang, P., Enkhjargal, B., Manaenko, A., Tang, J., Pearce, W.J., Hartman, R., Obenaus, A., Chen, G. and Zhang, J.H., 2016. Recombinant osteopontin stabilizes smooth muscle cell phenotype via integrin receptor/integrin-linked kinase/Rac-1 pathway after subarachnoid hemorrhage in rats. Stroke, 47(5), pp.1319-1327.

Yang, P., Wu, J., Miao, L., Manaenko, A., Matei, N., Zhang, Y., Xu, L., Pearce, W.J., Hartman, R.E., Obenaus, A. and Zhang, J.H., 2016. Platelet-derived growth factor receptor-β regulates vascular smooth muscle cell phenotypic transformation and neuroinflammation after intracerebral hemorrhage in mice. Critical care medicine, 44(6), pp.e390-e402.

Li, Y., Ma, Q., Halavi, S., Concepcion, K., Hartman, R.E., Obenaus, A., Xiao, D. and Zhang, L., 2016. Fetal stress-mediated hypomethylation increases the brain susceptibility to hypoxic–ischemic injury in neonatal rats. Experimental neurology, 275, pp.1-10.

Pearce, W.J., Doan, C., Carreon, D., Kim, D., Durrant, L.M., Manaenko, A., McCoy, L., Obenaus, A., Zhang, J.H. and Tang, J., 2016. Imatinib attenuates cerebrovascular injury and phenotypic transformation after intracerebral hemorrhage in rats. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 311(6), pp.R1093-R1104.

Kalyan-Masih, P., Vega-Torres, J.D., Miles, C., Haddad, E., Rainsbury, S., Baghchechi, M., Obenaus, A. and Figueroa, J.D., 2016. Western High-Fat Diet Consumption during Adolescence Increases Susceptibility to Traumatic Stress while Selectively Disrupting Hippocampal and Ventricular Volumes. eneuro, 3(5), pp.ENEURO-0125.

Nikolakopoulou, A.M., Koeppen, J., Garcia, M., Leish, J., Obenaus, A. and Ethell, I.M., 2016. Astrocytic ephrin-B1 regulates synapse remodeling following traumatic brain injury. ASN neuro, 8(1), p.1759091416630220.

Wu, J., Zhang, Y., Yang, P., Enkhjargal, B., Manaenko, A., Tang, J., Pearce, W.J., Hartman, R., Obenaus, A., Chen, G. and Zhang, J.H., 2016. rOsteopontin Stabilizes Smooth Muscle Cell Phenotype via Integrin Receptor/ILK/Rac-1 Pathway after SAH in Rats. Stroke; a journal of cerebral circulation, 47(5), p.1319.

Manaenko, A., Yang, P., Nowrangi, D., Budbazar, E., Hartman, R.E., Obenaus, A., Pearce, W.J., Zhang, J.H. and Tang, J., 2016. Inhibition of stress fiber formation preserves blood–brain barrier after intracerebral hemorrhage in mice. Journal of Cerebral Blood Flow & Metabolism, p.0271678X16679169.

Baghchechi, M., Plaia, A., Hamer, M., Ghosh, N., Ashwal, S. and Obenaus, A., 2016. Susceptibility-Weighted Imaging Identifies Iron-Oxide-Labeled Human Neural Stem Cells: Automated Computational Detection. Developmental Neuroscience, 38(6), pp.445-457.

McBride, D.W., Donovan, V., Hsu, M.S., Obenaus, A., Rodgers, V.G.J. and Binder, D.K., 2016. Reduction of Cerebral Edema via an Osmotic Transport Device Improves Functional Outcome after Traumatic Brain Injury in Mice. In Brain Edema XVI (pp. 285-289). Springer International Publishing.

Huang, L., Obenaus, A., Hamer, M. and Zhang, J.H., 2016. Neuroprotective effect of hyperbaric oxygen therapy in a juvenile rat model of repetitive mild traumatic brain injury. Medical gas research, 6(4), p.187.

Belayev, L., Khoutorova, L., Hong, S.H. and Obenaus, A., 2016. A novel therapeutic strategy for experimental stroke using docosahexaenoic acid complexed to human albumin. OCL, 23(1), p.D109.

Dashtipour, K., Liu, M., Kani, C., Dalaie, P., Obenaus, A., Simmons, D., Gatto, N.M. and Zarifi, M., 2015. Iron accumulation is not homogenous among patients with Parkinson’s disease. Parkinson’s Disease, 2015.

Barry, J.M., Choy, M., Dube, C., Robbins, A., Obenaus, A., Lenck-Santini, P.P., Scott, R.C., Baram, T.Z. and Holmes, G.L., 2015. T2 relaxation time post febrile status epilepticus predicts cognitive outcome. Experimental neurology, 269, pp.242-252.

Patterson, K.P., Brennan, G.P., Curran, M., Kinney-Lang, E., Dubé, C., Rashid, F., Ly, C., Obenaus, A. and Baram, T.Z., 2015. Rapid, coordinate inflammatory responses after experimental febrile status epilepticus: implications for epileptogenesis. Eneuro, 2(5), pp.ENEURO-0034.

Esfahani, E.T., McBride, D.W., Shafiei, S.B. and Obenaus, A., 2015. A Real-Time Analysis of Traumatic Brain Injury from T2 Weighted Magnetic Resonance Images Using a Symmetry-Based Algorithm. In Video Bioinformatics (pp. 99-117). Springer International Publishing.

Bianchi, A., Bhanu, B. and Obenaus, A., 2015. High-and Low-Level Contextual Modeling for the Detection of Mild Traumatic Brain Injury. In Video Bioinformatics (pp. 59-76). Springer International Publishing.

Ghosh, N., Ashwal, S. and Obenaus, A., 2015. Automated Identification of Injury Dynamics After Neonatal Hypoxia-Ischemia. In Video Bioinformatics (pp. 77-97). Springer International Publishing.

Obenaus, A., 2013. Neuroimaging biomarkers for epilepsy: advances and relevance to glial cells. Neurochemistry international, 63(7), pp.712-718.

Obenaus, A. and Ashwal, S., 2012. Neuroimaging of stroke and ischemia in animal models. Translational stroke research, 3(1), pp.4-7.

Obenaus, Andre, Nejmi Dilmac, Beatriz Tone, Hou Rou Tian, Richard Hartman, Murat Digicaylioglu, Evan Y. Snyder, and Stephen Ashwal. “Long‐term magnetic resonance imaging of stem cells in neonatal ischemic injury.” Annals of neurology 69, no. 2 (2011): 282-291.

Obenaus, A. and Hayes, P., 2011. Drill hole defects: induction, imaging, and analysis in the rodent. Embryonic Stem Cell Therapy for Osteo-Degenerative Diseases: Methods and Protocols, pp.301-314.

Obenaus, A., Huang, L., Smith, A., Favre, C.J., Nelson, G. and Kendall, E., 2008. Magnetic resonance imaging and spectroscopy of the rat hippocampus 1 month after exposure to 56Fe-particle radiation. Radiation research, 169(2), pp.149-161.

Obenaus, A. and Ashwal, S., 2008. Magnetic resonance imaging in cerebral ischemia: focus on neonates. Neuropharmacology, 55(3), pp.271-280.

Obenaus, A., Robbins, M., Blanco, G., Galloway, N.R., Snissarenko, E., Gillard, E., Lee, S. and Currás-Collazo, M., 2007. Multi-modal magnetic resonance imaging alterations in two rat models of mild neurotrauma. Journal of neurotrauma, 24(7), pp.1147-1160.

Obenaus, A. and Jacobs, R.E., 2007. Magnetic resonance imaging of functional anatomy: use for small animal epilepsy models. Epilepsia, 48(s4), pp.11-17.

Obenaus, A., Yong-Hing, C.J., Tong, K.A. and Sarty, G.E., 2001. A reliable method for measurement and normalization of pediatric hippocampal volumes. Pediatric research, 50(1), pp.124-132.

Obenaus, A., Esclapez, M. and Houser, C.R., 1993. Loss of glutamate decarboxylase mRNA-containing neurons in the rat dentate gyrus following pilocarpine-induced seizures. Journal of Neuroscience, 13(10), pp.4470-4485.