Overview
Active Studies
Mobile Health for Adherence in Breast Cancer Patients (CONCURxP)
This clinical trial compares the use of the connected customized treatment platform (CONCURxP), consisting of using a medication monitoring device called WiseBag along with text message reminders for missed or extra medication events, to enhanced usual care (EUC), where patients only use the WiseBag, to monitor medication adherence in patients with metastatic breast cancer who are taking a CKD4/6 inhibitor. To ensure CDK4/6 inhibitors achieve their full clinical benefit, patients need to take them as prescribed, following a complex treatment schedule. Forgetfulness was the most common reason reported for medication non adherence. Using the WiseBag along with CONCURxP or enhanced usual care may improve medication adherence in patients with metastatic breast cancer who are taking a CKD4/6 inhibitor.

Cost Communication and Financial Navigation in Cancer Patients (CostCOM)
Most cancer patients experience financial hardship as a direct result of receiving expensive cancer care and lost income. Our study will test the effectiveness of a multicomponent financial counseling program, CostCOM, that will help patients with newly diagnosed cancer at NCI community oncology research program (NCORP) practices across the United State to learn about their personalized treatment out-of-pocket costs using a price estimator tool, understand their insurance benefits, and receive financial navigation (e.g., get enrolled in financial assistance programs). We anticipate that CostCOM compared to enhanced usual care will improve cost-related cancer care nonadherence and quality of life and decrease material financial hardship and financial worry.

Empowering patients’ Lung Cancer Screening Uptake (Empower LCS)
Lung cancer is the leading cause of cancer-related mortality, with 1.8 million annual deaths worldwide. Lung cancer screening (LCS) with low-dose computed tomography (LDCT) is shown to decrease mortality rate of lung cancer by 20%, compared with chest x-ray alone. On the other hand, there are several barriers to LCS. Interventions addressing LCS knowledge barriers have shown an increase in patients’ knowledge or decisional certainty.
Goal
Our goal is to deliver a multi-level intervention including: (1) PCP notifications of patients’ LCS eligibility (addressing provider time constraints and barrier in identifying eligible patients); (2) patients’ education (addressing knowledge barriers); (3) patients’ referral to financial navigation resources (addressing health-related social risks); and (4) patients’ reminder to discuss LCS during PCP visit.
Impact
Adherence to lung cancer screening remains low with multiple contributing patient- and provider-level barriers. Effective interventions to address such barriers among diverse population and improve lung cancer screening adherence are lacking. Our study will assess perceptions and barriers towards lung cancer screening among a
diverse racial/ethnic population-some of whom receiving care in community health centers- and their providers. We will test feasibility of a multilevel intervention addressing patient and providers’ barriers and use a mixed-method approach to further refine our intervention for future larger effectiveness trials.
ClinicalTrails.Gov Registration
https://clinicaltrials.gov/study/NCT06000683?cond=empower%20lcs&rank=1: Research
Lung Cancer Screening Awareness Study
Goal
Our study aims at evaluating patients’ perceived risks, benefits and barriers to lung cancer screening in the diverse population being served by a single academic institution in Southern California. This will allow us to design interventions to address barriers to lung cancer screenings and improve lung cancer screening uptake
Impact
By finding the barriers and perceptions patients may face in ordering a lung cancer screening, we can design new interventions to help patients be informed of LCS and how to order one.

Empowering Hispanic Patients’ Lung Cancer Screening Uptake (Empower Latinx LCS)
Lung cancer is the leading cause of cancer-related mortality, with 1.8 million annual deaths worldwide. Lung cancer screening (LCS) with low-dose computed tomography (LDCT) is shown to decrease mortality rate of lung cancer by 20%, compared with chest x-ray alone. On the other hand, there are several barriers to LCS. This study alone focuses on the Latinx community and the possible interventions that can be done in order to increase LCS uptake in the Latinx community.
Goal
Our goal is to deliver a multi-level intervention in the Latinx community including: (1) PCP notifications of patients’ LCS eligibility (addressing provider time constraints and barrier in identifying eligible patients); (2) patients’ education (addressing knowledge barriers); (3) patients’ referral to financial navigation resources (addressing health-related social risks); and (4) patients’ reminder to discuss LCS during PCP visit. Alongside this intervention we will compare it to Enhanced Usual Care and its effects on LCS uptake.
Impact
Similar to Empower LCS study, this study will assess perceptions and barriers towards lung cancer screening among the Latinx population-some of whom are receiving care in community health centers- and their providers. We will test feasibility of our multi-level intervention to that of Enhanced Usual Care, and hopefully help patients in the Latinx community increase their lung cancer screening uptake.
