2025
- Sajjadi, S. A., Khan, Z., El‐Khoury, A., Bubbico, G., Akhlaghipour, G., Corrada, M. M., Kawas, C. H., & Paganini‐Hill, A. (2025). Association of language markers with future cognitive impairment and presence of limbic predominant age related TDP‐43 encephalopathy. Alzheimer’s & Dementia, 21(7), e70450. https://doi.org/10.1002/alz.70450.
- Woodworth, D. C., Lou, J. J., Yong, W. H., Head, E., Corrada, M. M., Nelson, P. T., & Sajjadi, S. A. (2025). Common neuropathologic change drivers of hippocampal sclerosis of ageing. Brain, awaf158.
- Ghanbarian, E., Khorsand, B., Petersen, K. K., Nallapu, B. T., Sajjadi, S. A., Lipton, R. B., Ezzati, A., & for the Alzheimer’s Disease Neuroimaging Initiative *. (2025). Cerebrospinal fluid inflammatory cytokines as prognostic indicators for cognitive decline across Alzheimer’s disease spectrum. Journal of Alzheimer’s Disease, 105(4), 1298–1308. https://doi.org/10.1177/13872877251335915.
- Demirsoy, I., Ghanbarian, E., Khorsand, B., Nallapu, B. T., Petersen, K. K., Lipton, R. B., Sajjadi, S. A., Rabin, L. A., & Ezzati, A. (2025). Association of item‐level responses to cognitive function index with tau pathology and hippocampal volume in the A4 Study. Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 17(2), e70128. https://doi.org/10.1002/dad2.70128.
2024
- Dutt, S., Woodworth, D. C., Sajjadi, S. A., Greenia, D. E., DeCarli, C., Kawas, C. H., Corrada, M. M., & Nation, D. A. (2024). Cerebral perfusion and amyloidosis in the oldest‐old. Alzheimer’s & Dementia, 20(12), 9068–9075. https://doi.org/10.1002/alz.14357.
- Woodworth, D. C., Greenia, D. E., Bukhari, S. A., Montine, T. J., Ezzati, A., Kawas, C. H., Corrada, M. M. M., & Sajjadi, S. A. (2024). Asymmetrical hippocampal atrophy: An arrow in the quiver of imaging markers for LATE‐NC. Alzheimer’s & Dementia, 20(S1), e090878. https://doi.org/10.1002/alz.090878.
- Fletcher, E., Sapkota, S., Martinez, O., Corrada, M. M. M., Woodworth, D. C., Sajjadi, S. A., & Decarli, C. (2024). Associations of cerebral amyloid and tau with neurocognitive performance: Findings from the 90+ Study. Alzheimer’s & Dementia, 20(S2), e093059. https://doi.org/10.1002/alz.093059.
- Woodworth, D. C., Nguyen, K. M., Sordo, L., Scambray, K. A., Head, E., Kawas, C. H., Corrada, M. M., Nelson, P. T., & Sajjadi, S. A. (2024). Evaluating the updated LATE‐NC staging criteria using data from NACC. Alzheimer’s & Dementia, 20(12), 8359–8373. https://doi.org/10.1002/alz.14262.
- Yu, J., Woodworth, D. C., Bukhari, S. A., Ezzati, A., Montine, T. J., Kawas, C. H., Corrada, M. M. M., Qian, T., & Sajjadi, S. A. (2024). Contribution of neuropathological changes to cognitive decline in late life; The 90+ Study. Alzheimer’s & Dementia, 20(S3), e091777. https://doi.org/10.1002/alz.091777.
- Sordo, L., Leiby, A. C., Malhas, R., Barlow, J., Rissman, R. A., Kawas, C. H., Corrada, M. M. M., Head, E., & Sajjadi, S. A. (2024). The potential of plasma TDP‐43 as a biomarker for limbic predominant age related TDP‐43 encephalopathy. Alzheimer’s & Dementia, 20(S2), e093180. https://doi.org/10.1002/alz.093180.
- Mobtahej, P., Gouron, S., Javaheri, R., El‐Khoury, A., Leiby, A. C., Sultzer, D. L., & Sajjadi, S. A. (2024). Transformer‐based Deep Learning Architecture Improves Detection of Associations between Spontaneous Speech Language Markers and Cognition. Alzheimer’s & Dementia, 20(S2), e089917. https://doi.org/10.1002/alz.089917.
- Mobtahej, P., Gouron, S., El‐Khoury, A., Leiby, A. C., Kawas, C. H., Corrada, M. M. M., & Sajjadi, S. A. (2024). Detection of Cognitive Impairment through Spontaneous Speech Acoustic Markers Using Transformer‐based Machine Learning Approach. Alzheimer’s & Dementia, 20(S2), e089873. https://doi.org/10.1002/alz.089873.
- Leiby, A. C., Farahmand, G., Ramanathan, A., Woodworth, D. C., Jiang, L., Yu, J., Qian, T., Corrada, M. M. M., Kawas, C. H., & Sajjadi, S. A. (2024). Serological inflammation markers and their association with cognition in the oldest old; The 90+ Study. Alzheimer’s & Dementia, 20(S3), e089918. https://doi.org/10.1002/alz.089918.
- Ritchie, M., Witbracht, M. G., Russ, E., Sajjadi, S. A., Thai, G., Tam, S., Gillen, D. L., & Grill, J. D. (2024). Utility of recruitment incentives in early Alzheimer’s disease clinical trials. Alzheimer’s & Dementia, 20(S6), e092808. https://doi.org/10.1002/alz.092808.
- Nallapu, B. T., Petersen, K. K., Demirsoy, I., Lipton, R. B., Davatzikos, C., Rabin, L., Sajjadi, S. A., & Ezzati, A. (2024). A weakly‐supervised, MRI‐guided clustering of cognitive decline: A post‐hoc analysis of the EXPEDITION‐3 clinical trial. Alzheimer’s & Dementia, 20(S9), e093891. https://doi.org/10.1002/alz.093891.
- Katsumata, Y., Wu, X., Aung, K. Z., Fardo, D. W., Woodworth, D. C., Sajjadi, S. A., Tomé, S. O., Thal, D. R., Troncoso, J. C., Chang, K., Mock, C., & Nelson, P. T. (2024). Pure LATE-NC: Frequency, clinical impact, and the importance of considering APOE genotype when assessing this and other subtypes of non-Alzheimer’s pathologies. Acta Neuropathologica, 148(1), 66. https://doi.org/10.1007/s00401-024-02821-y.
- Ritchie, M., Witbracht, M., Russ, E., Sajjadi, S. A., Thai, G. T., Tam, S., Gillen, D. L., & Grill, J. D. (2024). The utility of recruitment incentives in early Alzheimer’s disease trials. Alzheimer’s & Dementia, 20(9), 6654–6658. https://doi.org/10.1002/alz.14143.
- Wang, J., Ackley, S., Woodworth, D. C., Sajjadi, S. A., Decarli, C. S., Fletcher, E. F., Glymour, M. M., Jiang, L., Kawas, C., & Corrada, M. M. (2024). Associations of Amyloid Burden, White Matter Hyperintensities, and Hippocampal Volume With Cognitive Trajectories in the 90+ Study. Neurology, 103(3), e209665. https://doi.org/10.1212/WNL.0000000000209665.
- Woodworth, D. C., Nguyen, K. M., Sordo, L., Scambray, K. A., Head, E., Kawas, C. H., Corrada, M. M., Nelson, P. T., & Sajjadi, S. A. (2024). Comprehensive assessment of TDP-43 neuropathology data in the National Alzheimer’s Coordinating Center database. Acta Neuropathologica, 147(1), 103. https://doi.org/10.1007/s00401-024-02728-8.
- Yaghmaei, E., Lu, H., Ehwerhemuepha, L., Zheng, J., Danioko, S., Rezaie, A., Sajjadi, S. A., & Rakovski, C. (2024). Combined use of Donepezil and Memantine increases the probability of five-year survival of Alzheimer’s disease patients. Communications Medicine, 4(1), 99. https://doi.org/10.1038/s43856-024-00527-6.
- Ritchie, M., Sajjadi, S. A., & Grill, J. D. (2024). Apolipoprotein E Genetic Testing in a New Age of Alzheimer Disease Clinical Practice. Neurology Clinical Practice, 14(2), e200230. https://doi.org/10.1212/CPJ.0000000000200230.
- Cox, C. G., Salazar, C. R., Birnbaum, A. I., Witbracht, M., Tam, S. P., Thai, G. T., Sajjadi, S. A., Gillen, D. L., & Grill, J. D. (2024). Alzheimer’s Disease Biomarker Decision-Making among Patients with Mild Cognitive Impairment and Their Care Partners. The Journal of Prevention of Alzheimer’s Disease, 11(2), 285–293. https://doi.org/10.14283/jpad.2024.10.
2023
- Sordo, L., Qian, T., Nguyen, K. M., Bukhari, S. A., Woodworth, D. C., Montine, T. J., Head, E., Corrada, M. M. M., Kawas, C. H., & Sajjadi, S. A. (2023). Novel quantitative method for characterization of hippocampal sclerosis and its association with other neuropathologies and cognitive deficits. Alzheimer’s & Dementia, 19(S12), e079083. https://doi.org/10.1002/alz.079083.
- Woodworth, D. C., Nguyen, K. M., Bukhari, S. A., Montine, T. J., Kawas, C. H., Corrada, M. M. M., & Sajjadi, S. A. (2023). Association of LATE-NC with other neuropathologies and cognition in the oldest-old: Evidence from The 90+ Study and NACC. Alzheimer’s & Dementia, 19(S12), e079234. https://doi.org/10.1002/alz.079234.
- Corrada, M. M. M., Jiang, L., Sajjadi, S. A., Montine, T. J., Bukhari, S. A., Cholerton, B., Boyle, P. A., Brookmeyer, R., & Kawas, C. H. (2023). Proportion of Dementia Cases in the Oldest-old Attributable to 8 Neuropathological Changes: The 90+ Study. Alzheimer’s & Dementia, 19(S22), e074422. https://doi.org/10.1002/alz.074422.
- Melikyan, Z. A., Leiby, A.-M. C., Scambray, K. A., Nguyen, H. L., Basith, F., Fakhraee, S., Bukhari, S. A., Montine, T. J., Corrada, M. M. M., Kawas, C. H., & Sajjadi, S. A. (2023). Characteristics of oldest-old individuals with ‘Pure’ Limbic-predominant age-related TDP-43 encephalopathy: A 90+ Study case series. Alzheimer’s & Dementia, 19(S18), e078514. https://doi.org/10.1002/alz.078514.
- Biswas, R., Jiang, L., Kawas, C. H., Sajjadi, S. A., Montine, T. J., Bukhari, S. A., & Corrada, M. M. M. (2023). Association of individual and multiple comorbid neuropathologies with cognitive decline in the oldest-old: Results from The 90+ Study. Alzheimer’s & Dementia, 19(S12), e079461. https://doi.org/10.1002/alz.079461.
- Sajjadi, S. A., Yu, J., Qian, T., Bukhari, S. A., Montine, T. J., Corrada, M. M. M., & Kawas, C. H. (2023). Comparing longitudinal impact of LATE and Alzheimer’s neuropathologic changes in the oldest old. Alzheimer’s & Dementia, 19(S18), e077462. https://doi.org/10.1002/alz.077462.
- Woodworth, D. C., Li, J. X., Faramarzi, S., Greenia, D. E., Bukhari, S. A., Montine, T. J., Kawas, C. H., Corrada, M. M. M., & Sajjadi, S. A. (2023). Antemortem MRI detects atrophy related to hippocampal sclerosis pathology in the oldest-old but side matters: The 90+ Study. Alzheimer’s & Dementia, 19(S10), e081907. https://doi.org/10.1002/alz.081907.
- Woodworth, D. C., Nguyen, K. M., Kawas, C. H., Corrada, M. M. M., & Sajjadi, S. A. (2023). Gross measures of neurodegeneration from autopsy explain as much variance in dementia severity as measures from histology. Alzheimer’s & Dementia, 19(S12), e079477. https://doi.org/10.1002/alz.079477.
- Leiby, A. C., Scambray, K. A., Nguyen, H. L., Basith, F., Fakhraee, S., Melikyan, Z. A., Bukhari, S. A., Montine, T. J., Corrada, M. M., Kawas, C. H., & Sajjadi, S. A. (2023). Characterizing Limbic-Predominant Age-Related TDP-43 Encephalopathy Without Alzheimer’s Disease and Lewy Body Dementia in the Oldest Old: A Case Series. Journal of Alzheimer’s disease : JAD, 10.3233/JAD-230238. Advance online publication. https://doi.org/10.3233/JAD-230238.
- Yaghmaei, E., Pierce, A., Lu, H., Patel, Y. M., Ehwerhemuepha, L., Rezaie, A., Sajjadi, S. A., & Rakovski, C. (2023). A causal inference study: The impact of the combined administration of Donepezil and Memantine on decreasing hospital and emergency department visits of Alzheimer’s disease patients. PloS one, 18(9), e0291362. https://doi.org/10.1371/journal.pone.0291362.
- Li, J. X., Nguyen, H. L., Qian, T., Woodworth, D. C., Sajjadi, S. A., & Alzheimer’s Disease Neuroimaging Initiative (2023). Longitudinal hippocampal atrophy in hippocampal sclerosis of aging. Aging brain, 4, 100092. https://doi.org/10.1016/j.nbas.2023.100092.
- Sordo, L., Qian, T., Bukhari, S.A. et al. Characterization of hippocampal sclerosis of aging and its association with other neuropathologic changes and cognitive deficits in the oldest-old. Acta Neuropathol 146, 415–432 (2023). https://doi.org/10.1007/s00401-023-02606-9.
- Scambray, K. A., Nguyen, H. L., & Sajjadi, S. A. (2023). Association of vascular and degenerative brain pathologies and past medical history from the National Alzheimer’s Coordinating Center Database. Journal of neuropathology and experimental neurology, 82(5), 390–401. https://doi.org/10.1093/jnen/nlad020.
- Neuville, R. S., Biswas, R., Ho, C. C., Bukhari, S., Sajjadi, S. A., Paganini-Hill, A., Montine, T. J., Corrada, M. M., & Kawas, C. H. (2023). Study of neuropathological changes and dementia in 100 centenarians in The 90+ Study. Alzheimer’s & dementia : the journal of the Alzheimer’s Association, 19(8), 3417–3425. https://doi.org/10.1002/alz.12981.
- Paganini-Hill, A., Montine, T. J., Bukhari, S. A., Corrada, M. M., Kawas, C. H., & Sajjadi, S. A. (2023). LATE and potential estrogen-related risk factors collected 30 years earlier: The 90+ Study. Journal of neuropathology and experimental neurology, 82(2), 120–126. https://doi.org/10.1093/jnen/nlac119.
- Nelson, P. T., Lee, E. B., Cykowski, M. D., Alafuzoff, I., Arfanakis, K., Attems, J., Brayne, C., Corrada, M. M., Dugger, B. N., Flanagan, M. E., Ghetti, B., Grinberg, L. T., Grossman, M., Grothe, M. J., Halliday, G. M., Hasegawa, M., Hokkanen, S. R. K., Hunter, S., Jellinger, K., Kawas, C. H., … Neumann, M. (2023). LATE-NC staging in routine neuropathologic diagnosis: an update. Acta neuropathologica, 145(2), 159–173. https://doi.org/10.1007/s00401-022-02524-2.
- Sajjadi, S. A., Bukhari, S., Scambray, K. A., Yan, R., Kawas, C., Montine, T. J., & Corrada, M. M. (2023). Impact and Risk Factors of Limbic Predominant Age-Related TDP-43 Encephalopathy Neuropathologic Change in an Oldest-Old Cohort. Neurology, 100(2), e203–e210. https://doi.org/10.1212/WNL.0000000000201345.
2022
- Woodworth DC, Sheikh-Bahaei N, Scambray KA, Phelan MJ, Perez-Rosendahl M, Corrada MM, Kawas CH, Sajjadi SA; Alzheimer’s Disease Neuroimaging Initiative. Dementia is associated with medial temporal atrophy even after accounting for neuropathologies. Brain Commun. 2022 Mar 7;4(2):fcac052. doi: 10.1093/braincomms/fcac052. PMID: 35350552; PMCID: PMC8952251.
- Melikyan ZA, Corrada MM, Leiby AM, Sajjadi SA, Bukhari S, Montine TJ, Kawas CH. Cognitive resilience to three dementia-related neuropathologies in an oldest-old man: A case report from The 90+ Study. Neurobiol Aging. 2022 Aug;116:12-15. doi: 10.1016/j.neurobiolaging.2022.03.009. PMID: 35526514.
- Sajjadi SA, Bukhari S, Scambray K, Yan R, Kawas C, Montine TJ, Corrada MM. Impact and Risk Factors of Limbic Predominant Age-Related TDP-43 Encephalopathy Neuropathologic Change in an Oldest Old Cohort. Neurology. 2022 Oct 27:10.1212/WNL.0000000000201345. doi: 10.1212/WNL.0000000000201345. Epub ahead of print. PMID: 36302666.
2021
- Borders C, Sajjadi SA. Diagnosis and Management of Cognitive Concerns in the Oldest-Old. Curr Treat Options Neurol. 2021;23(3):10. doi: 10.1007/s11940-021-00665-5. Epub 2021 Mar 26. PMID: 33786000; PMCID: PMC7994350.
- Eslami-Amirabadi M, Sajjadi SA. The relation between thyroid dysregulation and impaired cognition/behaviour: An integrative review. J Neuroendocrinol. 2021 Mar;33(3):e12948. doi: 10.1111/jne.12948. PMID: 33655583; PMCID: PMC8087167.
- Sajjadi SA, Ash S, Cappa S. Preservation of Memory in Alzheimer-Related Primary Progressive Aphasia: Glass Half Full. Neurology. 2021 Feb 9;96(6):243-244. doi: 10.1212/WNL.0000000000011404. Epub 2021 Jan 13. PMID: 33441460.
2020
- Woodworth DC, Nguyen HL, Khan Z, Kawas CH, Corrada MM, Sajjadi SA. Utility of MRI in the identification of hippocampal sclerosis of aging. Alzheimers Dement. 2021 May;17(5):847-855. doi: 10.1002/alz.12241. Epub 2020 Dec 7. PMID: 33615673; PMCID: PMC8119299.
2017
- Bennett IJ, Greenia DE, Maillard P, Sajjadi SA, DeCarli C, Corrada MM, Kawas CH. Age-related white matter integrity differences in oldest-old without dementia. Neurobiol Aging. 2017 Aug;56:108-114. doi: 10.1016/j.neurobiolaging.2017.04.013. Epub 2017 Apr 26. PubMed PMID: 28527525; PubMed Central PMCID: PMC5647141.
- Grill JD, Apostolova LG, Bullain S, Burns JM, Cox CG, Dick M, Hartley D, Kawas C, Kremen S, Lingler J, Lopez OL, Mapstone M, Pierce A, Rabinovici G, Roberts JS, Sajjadi SA, Teng E, Karlawish J. Communicating mild cognitive impairment diagnoses with and without amyloid imaging. Alzheimers Res Ther. 2017 May 4;9(1):35. doi: 10.1186/s13195-017-0261-y. Review. PubMed PMID: 28472970; PubMed Central PMCID: PMC5418690.
- Hoffman P, Sajjadi SA, Patterson K, Nestor PJ. Data-driven classification of patients with primary progressive aphasia. Brain Lang. 2017 Nov;174:86-93. doi: 10.1016/j.bandl.2017.08.001. Epub 2017 Aug 10. PubMed PMID: 28803212; PubMed Central PMCID: PMC5626563.
- Sajjadi SA, Sheikh-Bahaei N, Cross J, Gillard JH, Scoffings D, Nestor PJ. Can MRI Visual Assessment Differentiate the Variants of Primary-Progressive Aphasia?. AJNR Am J Neuroradiol. 2017 May;38(5):954-960. doi: 10.3174/ajnr.A5126. Epub 2017 Mar 24. PubMed PMID: 28341715.
- Sheikh-Bahaei N, Sajjadi SA, Pierce AL. Current Role for Biomarkers in Clinical Diagnosis of Alzheimer Disease and Frontotemporal Dementia. Curr Treat Options Neurol. 2017 Nov 14;19(12):46. doi: 10.1007/s11940-017-0484-z. Review. PubMed PMID: 29134465.
- Paganini-Hill A, Greenia DE, Perry S, Sajjadi SA, Kawas CH, Corrada MM. Lower likelihood of falling at age 90+ is associated with daily exercise a quarter of a century earlier: The 90+ Study. Age Ageing. 2017 Nov 1;46(6):951-957. doi: 10.1093/ageing/afx039. PubMed PMID: 28369185; PubMed Central PMCID: PMC6267857.
2015
- Billette O, Sajjadi SA, Patterson K, Nestor PJ. SECT and MAST: new tests to assess grammatical abilities in primary progressive aphasia. Aphasiology. 2015; 29(10):1135-1151.
2014
- Diaz-de-Grenu LZ, Acosta-Cabronero J, Chong YF, Pereira JM, Sajjadi SA, Williams GB, Nestor PJ. A brief history of voxel-based grey matter analysis in Alzheimer’s disease. J Alzheimers Dis. 2014;38(3):647-59. doi: 10.3233/JAD-130362. PubMed PMID: 24037033.
- Sajjadi SA, Patterson K, Nestor PJ. Logopenic, mixed, or Alzheimer-related aphasia?. Neurology. 2014 Apr 1;82(13):1127-31. doi: 10.1212/WNL.0000000000000271. Epub 2014 Feb 26. PubMed PMID: 24574548.
2013
- Sajjadi SA, Acosta-Cabronero J, Patterson K, Diaz-de-Grenu LZ, Williams GB, Nestor PJ. Diffusion tensor magnetic resonance imaging for single subject diagnosis in neurodegenerative diseases. Brain. 2013 Jul;136(Pt 7):2253-61. doi: 10.1093/brain/awt118. Epub 2013 May 31. PubMed PMID: 23729473.
2012
- Sajjadi SA, Patterson K, Arnold RJ, Watson PC, Nestor PJ. Primary progressive aphasia: a tale of two syndromes and the rest. Neurology. 2012 May 22;78(21):1670-7. doi: 10.1212/WNL.0b013e3182574f79. Epub 2012 May 9. PubMed PMID: 22573633; PubMed Central PMCID: PMC3359509.
- Sajjadi SA, Patterson K, Tomek M, Nestor PJ. Abnormalities of connected speech in semantic dementia vs Alzheimer’s disease. Aphasiology. 2012; 26:847-866.
- Sajjadi SA, Patterson K, Tomek M, Nestor PJ. Abnormalities of connected speech in the non-semantic variants of primary progressive aphasia. Aphasiology. 2012; 26(10):1219-1237.
2006
- Sajjadi SA, Harirchian MH, Sheikhbahaei N, Mohebbi MR, Malekmadani MH, Saberi H. The relation between intracranial and intraocular pressures: study of 50 patients. Ann Neurol. 2006 May;59(5):867-70. doi: 10.1002/ana.20856. PubMed PMID: 16634008.
2004
- Larijani B, Bayat M, Khalili M, Sajjadi SA. Association between diabetes and depression. German journal of psychiatry. 2004; :62-65.