Publications

Journal Articles

  1. Iwobi, N., & Sparks, N. R. (2023). Endocrine Disruptor-Induced Bone Damage Due to Hormone Dysregulation: A Review. International Journal of Molecular Sciences, 24(9). https://doi.org/10.3390/ijms24098263
  2. McClelland DLV, Satoorian TS, Walker LM, Sparks NRL, Keller KC, Pulyanina PY, zur Nieden NI. (2016) Glucose-induced oxidative stress reduces proliferation in embryonic stem cells via FOXO3a/β-Catenin-dependent transcription of p21cip1. Stem Cell Reports. 7(1):55-68.2. https://doi.org/10.1016/j.stemcr.2016.06.006
  3. Keller KC, Ding H, Tieu R, Sparks NRL, Ehnes DD, zur Nieden NI. (2016) Wnt5a supports osteogenic lineage decisions in embryonic stem cells. Stem Cells Dev. 25(13):1020-32.3. https://doi.org/10.1089/scd.2015.0367
  4. Sparks NRL, Martinez IKC, Soto C, zur Nieden NI. (2018) Low osteogenic yield in human pluripotent stem cells associates with differential neural crest promoter methylation. Stem Cells. https://doi.org/10.1002/stem.2746
  5. Martinez IKC, Sparks NRL, Madrid JV, Affeldt H 3rd, Vera MKM, Bhanu B, zur Nieden NI. (2019) Video-based kinetic analysis of calcification in live osteogenic human embryonic stem cell cultures reveals the developmentally toxic effect of Snus tobacco extract. Toxicology and Applied Pharmacology. https://doi.org/10.1016/j.taap.2018.11.006
  6. Vliet SMF, Dasgupta S, Sparks NRL, Kirkwood JS, Vollaro A, Hur M, Zur Nieden NI, Volz DC. (2019) Maternal-to-zygotic transition as a potential target for niclosamide during early embryogenesis. Toxicol Appl Pharmacol. Aug 6:114699. https://doi.org/10.1016/j.taap.2019.114699
  7. Walker LM, Sparks NRL, Puig-Sanvicens V, Rodrigues B, zur Nieden NI. (2021) An Evaluation of Human Induced Pluripotent Stem Cells to Test for Cardiac Developmental Toxicity. Int J Mol Sci. Jul 29;22(15):8114.7. https://doi.org/10.3390/ijms22158114
  8. Martinez IKC, Sparks NRL, Madrid JV, Talbot P, zur Nieden NI. (2022) Exposure to cigarette smoke impedes human osteoblast differentiation independently of nicotine. Nicotine and Tobacco Research. Nov 12;24(12):1921-1926.8. https://doi.org/10.1093/ntr/ntac144
  9. Sparks NRL, Walker LM, Sera SR, Madrid JV, Hanna M, Dominguez EC, zur Nieden NI. (2022) Sidestream Smoke Extracts from Harm-Reduction and Conventional Camel Cigarettes Inhibit Osteogenic Differentiation via Oxidative Stress and Differential Activation of intrinsic Apoptotic Pathways. Antioxidants. ; 11(12):2474.https://doi.org/10.3390/antiox11122474

Books

  1. Sparks, N. R.L. and zur Nieden, N. I. (2014) Pluripotent Stem Cells as Tools to AssessDevelopmental Toxicity: Diversity Instead of Consolidation, in Handbook of Nanotoxicology, Nanomedicine and Stem Cell Use in Toxicology (eds S. C. Sahu and D. A. Casciano), John Wiley& Sons, Ltd, Chichester, UK. doi: 10.1002/9781118856017.ch16
  2. Madrid JV, Sera SR, Sparks NRL, zur Nieden NI. (2018) Human Pluripotent Stem Cells to Assess Developmental Toxicity in the Osteogenic Lineage. Methods Mol Biol. 1797:125-145