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About Us

Translational Imaging Lab (Zhuoli Zhang Lab) aims to develop novel treatment approaches which will further advance our knowledge and support our fight to cure cancer. As having all the state-of-the-art equipment for cancer research, our research group has focused on novel image-guided cancer immunotherapy including natural killer and dendritic cell-based immunotherapy, image-guided small molecular inhibitor and antibody immunotherapy, image-guided combination therapies of local ablation and targeted immunotherapy, image-guided drug delivery for cancer, and utilization of artificial intelligence for prediction of prognosis and evaluation of clinical outcomes. Our research team investigates rabbit, mouse, and rat tumor models to optimize and develop MRI sequences for the assessment of therapeutic response.

PI Zhuoli Zhang has extended experience and wide knowledge in setting up business models as well as drafting necessary documentation including Imaging Protocol Development, Imaging Acquisition Site Credentialing and Training, Quality Control (QC) protocol, and Image Analysis and Interpretation. Moreover, Dr. Zhuoli Zhang is in collaboration with other research groups by providing a comprehensive set of quantitative imaging services for clinical and research purposes, in particular in oncology and for evaluation of responses to cancer therapies.

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Selected Publications

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Irreversible electroporation ablation overcomes tumor-associated immunosuppression to improve the efficacy of DC vaccination in a mice model of pancreatic cancer

Yang J, Eresen A, Shangguan J, Ma Q, Yaghmai V, Zhang Z.

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Combination of NK-based immunotherapy and sorafenib against hepatocellular carcinoma

Yang J, Eresen A, Scotti A, Cai K, Zhang Z

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Correlation and Agreement of Yttrium-90 Positron Emission Tomography/Computed Tomography with Ex Vivo Radioembolization Microsphere Deposition in the Rabbit VX2 Liver Tumor Model

Gordon AC, Gates VL, White SB, Harris KR, Procissi D, Zhang Z, Li W, Samaan D, Nicolai JR, Mouli SK, Sato KT, Ryu RK, Omary RA, Salem R, Lewandowski RJ, Larson AC

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