Mitul MT, Kastenschmidt JM, Sureshchandra S, Wagoner ZW, Sorn AM, Mcllwain DR, Hernandez-Davies JE, Jain A, de Assis R, Trask D, Davies DH, Wagar LE. Tissue-specific sex differences in pediatric and adult immune cell composition and function. Front Immunol. 2024 May 15;15:1373537. PMID: 38812520; PMCID: PMC11133680.

Kastenschmidt JM*, Schroers-Martin J*, Sworder BJ, Sureshchandra S, Khodadoust MS, Liu CL, Olsen M, Kurtz DM, Diehn M, Wagar LE^†,Alizadeh AA^†. A human lymphoma organoid model for evaluating and targeting the follicular lymphoma tumor immune microenvironment. Cell Stem Cell. 2024 Mar 7;31(3):410-420.e4. PMID: 38402619. *equal contributions, ^†equal contributions

Kastenschmidt JM, Sureshchandra S, Wagar LE. Leveraging human immune organoids for rational vaccine design. Trends Immunol. 2023 Nov6:S1471-4906(23)00215-6. PMID: 37940395

Wagar LE. Human immune organoids: a tool to study vaccine responses. Nat Rev Immunol. 2023 Nov;23(11):699. PMID: 37803237.

Kastenschmidt JM, Sureshchandra S, Jain A, Hernandez-Davies JE, de Assis R, Wagoner ZW, Sorn AM, Mitul MT, Benchorin AI, Levendosky E, Ahuja G, Zhong Q, Trask D, Boeckmann J, Nakajima R, Jasinskas A, Saligrama N, Davies DH, Wagar LE. Influenza vaccine format mediates distinct cellular and antibody responses in human immune organoids. Immunity. 2023 Aug8;56(8):1910-1926.e7. PMID: 37478854.

Wagar L. Small centers of defense. Science. 2022 Feb 25;375(6583):830. PMID: 35201866.Wagar LE, Salahudeen A, Constantz CM, Wendel BS, Lyons MM, Mallajosyula V, Jatt LP, Adamska JZ, Blum LK, Gupta N, Jackson KJL, Yang F, Roltgen K, Roskin KM, Blaine KM, Meister KD, Ahmad IN, Cortese M, Dora EG, Tucker SN, Sperling AI, Jain A, Davies DH, Felgner PL, Hammer GB, Kim PS, Robinson WH, Boyd SD, Kuo CJ, Davis MM. Modeling human adaptive immune responses with tonsil organoids. Nat Med. 2021 Jan;27(1):125-135. doi: 10.1038/s41591-020-01145-0. Epub 2021 Jan 11. PubMed PMID: 33432170.

Salahudeen AA, Choi SS, Rustagi A, Zhu J, van Unen V, de la O SM, Flynn RA, Margalef-Catala M, Santos AJM, Ju J, Batish A, Usui T, Zheng GXY, Edwards CE, Wagar LE, Luca V, Anchang B, Nagendran M, Mguyen K, Hart DJ, Terry JM, Belgrader P, Ziraldo SB, Mikkelsen TS, Harbury PB, Glenn JS, Garcia KC, Davis MM, Baric RS, Sabatti C, Amieva MR, Blish CA, Desai TJ, Kuo CJ. Progenitor identification and SARS-CoV-2 infection in human distal lung organoids. Nature. 2020 Dec;588(7839):670-675. doi: 10.1038/s41586-020-3014-1. Epub 2020 Nov 25. Pubmed PMID: 33238290.

Glass DR, Tsai AG, Oliveria JP, Hartmann FJ, Kimmey SC, Calderon AA, Borges L, Glass MC, Wagar LE, Davis MM, Bendall SC. An Integrated Multi-omic Single-Cell Atlas of Human B Cell Identity. Immunity. 2020 Jul 14;53(1):217-232.e5. doi: 10.1016/j.immuni.2020.06.013. PubMed PMID: 32668225; PubMed Central PMCID: PMC7369630.

Chen B, Khodadoust MS, Olsson N, Wagar LE, Fast E, Liu CL, Muftuoglu Y, Sworder BJ, Diehn M, Levy R, Davis MM, Elias JE, Altman RB, Alizadeh AA. Predicting HLA class II antigen presentation through integrated deep learning. Nat Biotechnol. 2019 Nov;37(11):1332-1343. doi: 10.1038/s41587-019-0280-2. Epub 2019 Oct 14. PubMed PMID: 31611695; PubMed Central PMCID: PMC7075463.

Wagar LE, Bolen CR, Sigal N, Lopez Angel CJ, Guan L, Kirkpatrick BD, Haque R, Tibshirani RJ, Parsonnet J, Petri WA Jr, Davis MM. Increased T Cell Differentiation and Cytolytic Function in Bangladeshi Compared to American Children. Front Immunol. 2019;10:2239. doi: 10.3389/fimmu.2019.02239. eCollection 2019. PubMed PMID: 31620139; PubMed Central PMCID: PMC6763580.

Nielsen SCA, Roskin KM, Jackson KJL, Joshi SA, Nejad P, Lee JY, Wagar LE, Pham TD, Hoh RA, Nguyen KD, Tsunemoto HY, Patel SB, Tibshirani R, Ley C, Davis MM, Parsonnet J, Boyd SD. Shaping of infant B cell receptor repertoires by environmental factors and infectious disease. Sci Transl Med. 2019 Feb 27;11(481). doi: 10.1126/scitranslmed.aat2004. PubMed PMID: 30814336; PubMed Central PMCID: PMC6733608.

Wagar LE. Live Cell Barcoding for Efficient Analysis of Small Samples by Mass Cytometry. Methods Mol Biol. 2019;1989:125-135. doi: 10.1007/978-1-4939-9454-0_9. PubMed PMID: 31077103.

Wagar LE, DiFazio RM, Davis MM. Advanced model systems and tools for basic and translational human immunology. Genome Med. 2018 Sep 28;10(1):73. doi: 10.1186/s13073-018-0584-8. Review. PubMed PMID: 30266097; PubMed Central PMCID: PMC6162943.

Alcántara-Hernández M, Leylek R, Wagar LE, Engleman EG, Keler T, Marinkovich MP, Davis MM, Nolan GP, Idoyaga J. High-Dimensional Phenotypic Mapping of Human Dendritic Cells Reveals Interindividual Variation and Tissue Specialization. Immunity. 2017 Dec 19;47(6):1037-1050.e6. doi: 10.1016/j.immuni.2017.11.001. Epub 2017 Dec 5. PubMed PMID: 29221729; PubMed Central PMCID: PMC5738280.

Zhou AC, Wagar LE, Wortzman ME, Watts TH. Intrinsic 4-1BB signals are indispensable for the establishment of an influenza-specific tissue-resident memory CD8 T-cell population in the lung. Mucosal Immunol. 2017 Sep;10(5):1294-1309. doi: 10.1038/mi.2016.124. Epub 2017 Jan 4. PubMed PMID: 28051085.

Glanville J, Huang H, Nau A, Hatton O, Wagar LE, Rubelt F, Ji X, Han A, Krams SM, Pettus C, Haas N, Arlehamn CSL, Sette A, Boyd SD, Scriba TJ, Martinez OM, Davis MM. Identifying specificity groups in the T cell receptor repertoire. Nature. 2017 Jul 6;547(7661):94-98. doi: 10.1038/nature22976. Epub 2017 Jun 21. PubMed PMID: 28636589; PubMed Central PMCID: PMC5794212.

Khodadoust MS, Olsson N, Wagar LE, Haabeth OA, Chen B, Swaminathan K, Rawson K, Liu CL, Steiner D, Lund P, Rao S, Zhang L, Marceau C, Stehr H, Newman AM, Czerwinski DK, Carlton VE, Moorhead M, Faham M, Kohrt HE, Carette J, Green MR, Davis MM, Levy R, Elias JE, Alizadeh AA. Antigen presentation profiling reveals recognition of lymphoma immunoglobulin neoantigens. Nature. 2017 Mar 30;543(7647):723-727. doi: 10.1038/nature21433. Epub 2017 Mar 22. PubMed PMID: 28329770; PubMed Central PMCID: PMC5808925.

Qi Q, Cavanagh MM, Le Saux S, Wagar LE, Mackey S, Hu J, Maecker H, Swan GE, Davis MM, Dekker CL, Tian L, Weyand CM, Goronzy JJ. Defective T Memory Cell Differentiation after Varicella Zoster Vaccination in Older Individuals. PLoS Pathog. 2016 Oct;12(10):e1005892. doi: 10.1371/journal.ppat.1005892. eCollection 2016 Oct. PubMed PMID: 27764254; PubMed Central PMCID: PMC5072604.

Wagar LE, Rosella L, Crowcroft N, Lowcock B, Drohomyrecky PC, Foisy J, Gubbay J, Rebbapragada A, Winter AL, Achonu C, Ward BJ, Watts TH. Humoral and cell-mediated immunity to pandemic H1N1 influenza in a Canadian cohort one year post-pandemic: implications for vaccination. PLoS One. 2011;6(11):e28063. doi: 10.1371/journal.pone.0028063. Epub 2011 Nov 23. PubMed PMID: 22132212; PubMed Central PMCID: PMC3223223.

Wagar LE, Gentleman B, Pircher H, McElhaney JE, Watts TH. Influenza-specific T cells from older people are enriched in the late effector subset and their presence inversely correlates with vaccine response. PLoS One. 2011;6(8):e23698. doi: 10.1371/journal.pone.0023698. Epub 2011 Aug 22. PubMed PMID: 21887299; PubMed Central PMCID: PMC3161762.