Month: June 2025

Post doctoral fellows Ghazaleh Eskandari-Sedighi and Jean Paul Chadarevian attend the 2025 Alzheimer’s Disease: Multimodal Approaches to Mechanisms and Therapeutic Targets. In attendance were former MBJ lab members Emma Danhesh and Dr. Christel Claes. During the Functional Genomics and Alzheimer’s Disease session led by Dr. Celeste Karch, Dr. Ghazaleh presented “A Chimeric Mouse Model of Alzheimer’s Disease With Combined Amyloid and Tau Pathologies to Study Protective Human Microglia Responses in the Context of Disease“. Session included discussions on Systems Biology and Alzheimer’s Disease, Neuroimaging and Alzheimer’s Disease Models and Endophenotypes, AI and Machine Learning in AD, Epigenetics and Multi-Omics, Population and Sex Differences in Alzheimer’s Disease, and Therapeutic Approaches. Congratulations to chairs, Dr. Olivier Lichtarge and Dr. Towfique Raj, on an outstanding conference!

The Blurton-Jones lab celebrates and bids farewell to our Undergraduate Technician, Joia, as she begins the next chapter of her scientific studies as a graduate student at Harvard University.

Dr. Jean Paul Chadarevian presents “Engineering iPSC-derived Microglia for Immune Cell-based Therapies for Neurological Disorders” at the ISSCR 2025 Annual Meeting held in Hong Kong from 11-14 June 2025. His session Expanding Therapeutics through Stem Cells and Reprogramming was chaired by Dr. Athanasia D. Panopoulos of Cedars-Sinai Medical Center, and included concurrent talks from Dr. Maria Pia Cosma, Professor at the Centre for Genomic Regulation, and Dr. Pentao Liu, Professor of the University of Hong Kong.

The Guojun Bu Laboratory also hosted Dr. Chadarevian at the Hong Kong University of Science and Technology.

The University of California, Irvine Institute for Memory Impairments and Neurological Disorders (UCI MIND) is proud to announce that postdoctoral fellow Jean Paul Chadarevian, PhD, has been awarded a prestigious grant from the Larry L. Hillblom Foundation. The three-year, $225,000 award will support Dr. Chadarevian’s innovative research into the role of peripheral immune cells in the development and progression of Alzheimer’s disease (AD). Working in the laboratory of Dr. Mathew Blurton-Jones, Professor of Neurobiology and Behavior at UCI, Dr. Chadarevian will investigate how immune cells that originate outside the brain infiltrate it and contribute to the disease’s pathology.

Read more here.