2023
Watanabe M, Tsai Y, Ozaki H, Morikawa A, Shiraiwa K, Pin A, Salem A, Phommahasay K, Sugita B, Vu C, Hammad S, Kamei K. “Brain Organoid-on-a-Chip to Create Multiple Domains in Forebrain Organoids.” BioRxiv, January 1, 2023, 2023.09.18.558278. https://doi.org/10.1101/2023.09.18.558278.
2022
Watanabe M, Buth JE, Haney JR, Vishlaghi N, Turcios F, Elahi LS, Gu W, Pearson CA, Kurdian A, Baliaouri NV, Collier AJ, Miranda OA, Dunn N, Chen D, Sabri S, Torre-Ubieta L. de, Clark AT, Plath K, Christofk HR, Novitch BG (2022). TGFΒ superfamily signaling regulates the state of human stem cell pluripotency and capacity to create well-structured telencephalic organoids. Stem Cell Reports. 2022 October 11;17(10), 2220–2238. https://doi.org/10.1016/j.stemcr.2022.08.013
2021
Taniguchi-Ikeda M, Koyanagi-Aoi M, Maruyama T, Takaori T, Hosoya A, Tezuka H, Nagase S, Ishihara T, Kadoshima T, Muguruma K, Ishigaki K, Sakurai H, Mizoguchi A, Novitch BG, Toda T, Watanabe M, Aoi T. Restoration of the defect in radial glial fiber migration and cortical plate organization in a brain organoid model of Fukuyama muscular dystrophy. IScience. 2021 October 22;24(10):103140. doi: https://doi.org/10.1016/j.isci.2021.103140.
Samarasinghe RA, Miranda OA, Mitchell S, Fernando I, Watanabe M, Buth JE, Kurdian A, Golshani P, Plath K, Lowry WE, Parent JM, Mody I, Novitch BG. Identification of neural oscillations and epileptiform changes in human brain organoids. Nature Neuroscience. 2021 August 23. doi: https://doi.org/10.1101/82 0183.
Sawai T, Hayashi Y, Niikawa T, Shepherd J, Thomas E, Lee TL, Erler A, Watanabe M, Sakaguchi H. Mapping the Ethical Issues of Brain Organoid Research and Application. AJOB Neuroscience. 2021 March 26. doi: https://doi.org/10.1080/21507740.2021. 1896603.
2017
Watanabe M, Buth JE, Vishlagi N, Torre-Ubieta L, Taxidis J, Khakh BS, Coppola G, Pearson CA, Yamauchi K, Gong D, Dai X, Damoiseaux R, Aliyari R, Liebscher S, Schenke-Layland K, Caneda C, Huang EJ, Zhang Y, Novitch BG. Self-organized cerebral organoids with human-specific features predict effective drugs to combat Zika virus infection. Cell Reports. 2017 October 10;21(2):517-532. doi: https://doi.org/10.1016/j.celrep.2017.09.047.
Li C, Deng YQ, Wang S, Ma F, Aliyari R, Huang XY, Zhang NN, Watanabe M, Dong HL, Liu P, Li XF, Ye Q, Tian M, Hong S, Fan J, Zhao H, Li L, Vishlagi N, Buth JE, Au C, Liu Y, Lu N, Du P, Qin XF, Zhang B, Gong D, Dai X, Sun R, Novitch BG, Xu Z, Qin CF, Cheng G. 25-Hydroxycholesterol protects host against Zika virus infection and its associated microcephaly in a mouse model. Immunity. 2017 March 21;46(3):446-456. doi: https://doi.org/10.1016/ j.immuni.2017.02.012.
2016
Watanabe M. Fung ES, Chan FB, Wong JS, Coutts M, Monuki ES. BMP4 acts as a dorsal telencephalic morphogen in a mouse embryonic stem cell culture system. Biology Open. 2016;5:1834-1843. doi: 10.1242/bio.012021.
2015
Lun MP, Johnson MB, Broadbelt KG, Watanabe M, Kang YJ, Chau KF, Springel MW, Malesz A, Sousa AMM, Pletikos M, Adelita T, Calicchio ML, Zhang Y, Holtzman MJ, Lidov HGW, Sestan N, Steen H, Monuki ES, Lehtinen MK. Spatially heterogeneous choroid plexus transcriptomes encode positional identity and contribute to regional CSF production. Journal of Neuroscience. 25 March 2015;35(12):4903-4916. doi:10.1523/JNEUROSCI. 3081-14.2015.
2014
Watanabe M, Monuki ES. (2014). Generation of Choroid Plexus Epithelial Cells from Human Embryonic Stem Cells. US Patent No. 8,748,176B2. Oakland, CA. The Regents of the University of California.
2013
Watanabe M. Bmp4 as a Classic Morphogen for Deriving Dorsal Telencephalic Midline Fates from Embryonic Stem Cells. 2013.
2012
Watanabe M, Kang YJ, Davies LM, Meghpara S, Lau K, Chung CY, Kathiriya J, Hadjantonakis AK, Monuki ES. BMP4 sufficiency to induce choroid plexus epithelial fate from embryonic stem cell-derived neuroepithelial progenitors. Journal of Neuroscience. 7 November 2012;32(45):5934-15945. doi: https://doi.org/10.1523/JNEUROSCI.3227-12.2012.
2011
Biswas M, Phan D, Watanabe M, and Chan JY. The Fbw7 Tumor Suppressor Regulates Nuclear Factor E2-related Factor 1 Transcription Factor Turnover through Proteasome-mediated Proteolysis. Journal of Biological Chemistry. 11 November 2011;286:39282-39289. doi:10.1074/jbc.M111.253807.
Nakano I, Joshi K, Visnyei K, Hu B, Watanabe M, Lam D, Wexler E, Saigusa K, Nakamura Y, Laks DR, Mischel PS, Viapiano M, Kornblum HI. Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway. Neuro-Oncology. June 2011;13(6):622–634. doi: https://doi.org/10.1093/ neuonc/nor023.
Watanabe M, Monuki ES. Embryonic Stem Cell-Derived Choroid Plexus Epithelial Cells: A Potential Therapy for Alzheimer’s Disease. Journal of Neuropathology and Experimental Neurology.2011;70(6):517.
2007
Nakano I, Masterman‐Smith M, Saigusa K, Paucar AA, Horvath S, Shoemaker L, Watanabe M, Negro A, Bajpai R, Howes A, Lelievre V, Waschek JA, Lazareff JA, Freije WA, Liau LM, Gilbertson RJ, Cloughesy TF, Geschwind DH, Nelson SF, Mischel PS, Terskikh AV, Kornblum HI. Maternal embryonic leucine zipper kinase is a key regulator of the proliferation of malignant brain tumors, including brain tumor stem cells. Journal of Neuroscience Research. 2007 April 24;86(1):48–60. https://doi.org/10.1002/jnr.21471.
