News
NRM 2021 December 14-16
The Lab presented several projects at the NEURORECEPTOR MAPPING MEETING, 2021
[18F]Flotaza and [124I]IBETA, two new β-amyloid PET imaging agents in post-mortem human Alzheimer’s disease brain (#317)
Presentation type: Poster (Poster)
Presenter: An N. Nguyen [YOUNG INVESTIGATOR AWARD]
Presentation was accepted on 29 November, 2021, 12:43 PM by An N. Nguyen
Increased Tau, Aβ Amyloid, and Monoamine Oxidase-A in Post-Mortem Human Alzheimer’s Disease Anterior Cingulate (#330)
Presentation type: Oral Talks (Oral)
Session: S-03 — Oral Talks 3
Date: Thursday, 16 December, 2021, 9:30 AM – 12:15 PM
Presenter: Amina U. Syed
Presentation was accepted on 30 November, 2021, 3:11 PM by Amina U. Syed
Comparative Analysis of Immunohistochemical and Autoradiographic Images of Tau in Postmortem Human Alzheimer’s Disease Brain (#308)
Presentation type: Poster (Poster)
Presenter: Rommani Mondal [YOUNG INVESTIGATOR AWARD]
Presentation was accepted on 30 November, 2021, 2:36 PM by Rommani Mondal
Comparison of Lewy body distribution and monoamine oxidase A in anterior cingulate of postmortem Parkinson’s disease brains (#286)
Presentation type: Poster (Poster)
Presenter: Reisha M. Ladwa
Presentation was accepted on 10 December, 2021, 11:40 PM by Reisha M. Ladwa
[124I]IPPI: Molecular modeling and autoradiographic study for binding to Taupathies (#329)
Presentation type: Poster (Poster)
Presenter: Taylor R. Moran [STUDENT AWARD]
Presentation was accepted on 30 November, 2021, 12:29 PM by Taylor R. Moran
[124I]IAZA: Development of a New Radioiodinated PET Imaging Agent for Human Alzheimer’s Disease Brain (#406)
Presentation type: Poster (Poster)
Presenter: Thrisha T. Reddy
Presentation was accepted on 30 November, 2021, 3:28 PM by Thrisha T. Reddy
[124I]IBETA PET/CT Studies in Alzheimer’s Disease 5XFAD Mouse Model of β-amyloid (Aβ) Plaques (#279)
Presentation type: Poster (Poster)
Presenter: Christopher Liang
Presentation was accepted on 29 November, 2021, 12:26 PM by Christopher Liang
WMIC, October 5-8, 2021
[125I]IAZA: A New Imaging Agent for Human Alzheimer’s Disease Brain
Presented by Thisha Reddy
Poster Session 1: Neuroscience Probes & Targets
SNMMI Annual Meeting, June 12-15, 2021
Following Meeting abstracts will be presented at the meeting:
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…[ 18 F]Fluoroethylharmol: Improved Radiosynthesis and Evaluation of Monoamine Oxidase-A inAlzheimers and Parkinsons Disease Amina Syed 1 , Christopher Liang 1 and Jogeshwar Mukherjee 1 1 Radiological Sciences University of California Irvine CA United States View larger version: In this window …
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[18F]FDG PET/CT Studies in Parkinson’s Disease Mouse Model of α-Syncleinopathy
…[ 18 F]FDG PET/CT Studies in Parkinsons Disease Mouse Model of -Syncleinopathy Anthony Campoy 1 , Rommani Mondal 1 , Christopher Liang 1 and Jogeshwar Mukherjee 1 1 University of California Irvine CA United States View larger version: In this window In a new window View larger version … -
[18F]Nifene PET/CT Studies in Parkinson’s Disease A53T Mouse Model of a-Syncleinopathy
…[ 18 F]Nifene PET/CT Studies in Parkinsons Disease A53T Mouse Model of a-Syncleinopathy Christopher Liang 1 , Anthony Campoy 1 , Rommani Mondal 1 and Jogeshwar Mukherjee 1 1 Radiological Sciences, University of California Irvine CA United States View larger version: In this window In a new window … -
…Monoamine Oxidase-A is Upregulated in Post-Mortem Human Alzheimers Disease and Parkinsons Disease Brain Jogeshwar Mukherjee 1 , Christopher Liang 1 , Amina Syed 1 , Phuc Lam 1 , Rommani Mondal 1 , Tonya Mukherjee 1 and Krystal Patel 1 1 Radiological Sciences University of California-Irvine Irvine …
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…Evaluation of [ 18 F]Flotaza, a new-amyloid PET imaging agent in post-mortem human Alzheimers disease brain and 5XFAD transgenic mice Harsimran Kaur 1 , Megan Felix 1 , An Nguyen 1 , Amina Syed 1 , Christopher Liang 1 and Jogeshwar Mukherjee 1 1 University of California Irvine CA United States …
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…2* receptors is reduced in postmortem Alzheimers disease brains 1 Radiological Sciences University of California-Irvine Irvine CA United States 2 Radiological Sciences Univ of Calfornia – Irvine Irvine CA United States Mukherjee Jogeshwar 1 Liang Christopher 1 Campoy Anthony 1 Kaur Harsimran 1 Syed …
UROP UCI Symposium_ May 21, 2021
Following Student Researchers presented their work at this years symposium:
Phuc Lam
Megan R. Felix
Anthony Campoy
Harsimran Kaur
Tram Danh
Rommani Mondal
Amina U. Syed
Flotaza for Alzheimer’s disease, June 9, 2021
PET radiotracer tweaked for greater precision in AD detection
By Will Morton, AuntMinnie.com staff writer
June 9, 2021 — A new PET radiotracer based on previously studied radiopharmaceuticals may improve the detection of beta amyloid plaques seen in Alzheimer’s disease, according to a study published in the August (in progress) issue of Bioorganic & Medicinal Chemistry Letters.
https://www.auntminnie.com/index.aspx?sec=ser&sub=def&pag=dis&ItemID=132627
GE TracerLab FXN Installed 12/01/2020
World Molecular Imaging Conference (WMIC), 10/7/2020
FOLLOWING FOUR PRESENTATIONS BY OUR LAB MEMBERS AT THIS MEETING:
Christopher Liang, Phuc Lam, Rommani Mondal, Anthony Campoy, Tram Danh, Stephanie Martinez, Jogeshwar Mukherjee.
[18F]FAZIN3: Novel Monoamine Oxidase-A PET Reversible Radiotracer shows Upregulation in Post-Mortem Human Alzheimer’s and Parkinson’s Disease.
Rommani Mondal, Christopher Liang, Anthony Campoy, Phuc Lam, Tram Danh, Jogeshwar Mukherjee.
PET Studies in Transgenic Hualpha-Syn(A53T) Parkinson’s Disease Mouse Model of a-Syncleinopathy.
Harsimran Kaur, Megan Rose Felix, Christopher Liang, Jogeshwar Mukherjee.
[18F]Flotaza: A New b-Amyloid PET Imaging Agent in Post-Mortem Human Alzheimer’s Disease Brain.
Jogeshwar Mukherjee, Christopher Liang, Krystal Patel, Phuc Lam, Rommani Mondal.
[125I]IPPI for tau imaging in post-mortem human Alzheimer’s disease brain.
SNMMI Virtual Annual Meeting 2020, July 11-14
Annual Meeting of Society of Nuclear Medicine and Molecular Imaging, July 11-14, 2020 (Virtual Meeting).
THE FOLLOWING 3 PRESENTATIONS WERE MADE BY THE LAB RESERACHERS:
Liang, C., Lam, P.Q., Martinez, S., Mukherjee J.
Development of [18F]FAZIN3 for PET imaging of neurofibrillary tangles in Alzheimer’s disease. Journal of Nuclear Medicine, Vol. 61, Supplement 1, 1032, 2020.
Lam, P.Q., Martinez, S., Liang, C., Patel, K.K., Mukherjee J.
[18F]FAZIN3: A novel PET imaging agent for Parkinson’s disease. Journal of Nuclear Medicine, Vol. 61, Supplement 1, 148, 2020.
Campoy, A., Danh, T., Patel, K.K., Kaur, H., Liang, C., Mukherjee J.
[18F]Nifene binding to Nicotinic a4b2* receptors in anterior cingulate of postmortem human Alzheimer’s disease brain. Journal of Nuclear Medicine, Vol. 61, Supplement 1, 1537, 2020.
Metz Lectures, University of Chicago, Feb 4 and 5, 2020
https://biologicalsciences.uchicago.edu/event/neuroreceptor-pet-imaging-agents-design-animal-models-human-studies