On Wed Nov 18 at 10:00 am Dr. Tom Lu will present:
Sedley, W., Parikh, J., Edden, R. A. E., Tait, V., Blamire, A., & Griffiths, T. D. (2015). Human Auditory Cortex Neurochemistry Reflects the Presence and Severity of Tinnitus. The Journal of Neuroscience : The Official Journal of the Society for Neuroscience, 35(44), 14822–8. doi:10.1523/JNEUROSCI.2695-15.2015
GABA concentration was reduced in relatively mild tinnitus sufferers’ auditory cortex – producing less inhibition then more excitation – imbalance or increased central noise that might be responsible for tinnitus.
This network balance or noise interpretation is consistent with a recent study by Dietmar Basta “Bilateral Changes of Spontaneous Activity Within the Central Auditory Pathway Upon Chronic Unilateral Intracochlear Electrical Stimulation.” Otology and Neurotology, 2015.