Christofer Sanchez officially started on 09/19/2022 as our first full-time recruit. Christofer received his bachelor’s degree from UC Riverside, where he graduated summa cum laude with a B.S. in Biochemistry. He will be focusing primarily on our endocytosis project and helping with lab management. Welcome, Chris!!!
News
New funding! NIAID DP2 Grant
Haik has been awarded a $2.31M grant from the National Institute of Allergy and Infectious Diseases (NIAID). The five-year “New Innovators Award” (DP2) will be used to study how N-glycan branching and endocytosis pathways interact to regulate receptor turnover at the plasma membrane.
More information can be found here: https://reporter.nih.gov/search/pl3Nx5CF7kmwMvcq4xfs4w/project-details/10295564
We are immediately looking for graduate students, post-docs, and/or full-time staff to work on this project. Please contact Haik at haik.m@uci.edu for more information.
New Article Published
Our work on N-glycosylation and T cell aging has been published in Nature Aging. In this paper we present a new explanation (altered N-glycan branching on T cells) for why the immune system weakens with age. We also show that this is driven by increased cytokine signaling (interleukin-7) and elevated levels of a normal metabolite (n-acetylglucosamine). Interestingly, this age-associated change is sex dimorphic, with a greater effect in older women than men. Correcting/reversing this change might help protect older adults from infections and cancer.
Read more here:
Mkhikian Lab Established
The Mkhikian Lab is established in the Pathology Department at UCI on March 01, 2022. We are located in rooms D468, D470 and D476 of the Medical Sciences I building.