Batool Rizvi

Graduate Student
Email: brizvi@uci.edu
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About Me

Projects

Research Interests

Publications

Fun!

I received my B.A. in Psychology from UC Berkeley, and an M.S. in Neuroscience and Education from Columbia University (Teachers College). While at UC Berkeley, I was an undergraduate research assistant for three years in Dr. Mark D’Esposito’s neuroimaging lab. While I was there, I completed my honors thesis titled, “Investigating the Impact of Structural Changes in White Matter Pathways on Executive Control Performance in Healthy Aging”. After graduating, I was a volunteer RA in Dr. Adam Gazzaley’s lab at UCSF, where I administered cognitive tasks and a battery of neuropsychological tests. I proceeded to obtain my Master’s degree in Neuroscience and Education at Columbia University. During this time, I also worked full time as an Imaging Analyst at Dr. Adam Brickman’s lab at Columbia, doing research on various structural MR imaging measures of cerebrovascular disease and neurodegeneration in older adults. Currently, at UCI, I am a PhD student through the Interdepartmental Neuroscience Program. In Dr. Yassa’s lab, I am studying the effects of vascular markers (such as white matter hyperintensities) on structural and functional measures, Alzheimer’s pathology, and memory.

I contribute to the following research areas in the Translational Neuroscience Laboratory.

I am interested in the intersections between vascular disease, aging, and Alzheimer’s disease (AD) pathology. As a reflection of small vessel cerebrovascular disease, white matter hyperintensities (WMH) can be measured through MR imaging, are strongly linked to cognitive impairment including age-related memory decline. With my background and interest in specifically WMH, I hope to ask questions related to how WMH burden and its spatial characteristics can predict risk to AD, and markers of tau and neurodegeneration. I would be further interested in understanding neurobiological mechanisms underlying AD onset and progression in individuals with Down syndrome.

Rizvi, B., Lao, P.J., Colon, J.M., Hale, C., Igwe, K.C., Narkhede, A., Budge, M., Manly, J.J., Schupf, N., & Brickman, A.M. (in press). Tract-defined regional white matter hyperintensities and memory. Neuroimage: Clinical.

Rizvi, B., Narkhede, A., Last, B. S., Budge, M., Tosto, G., Manly, J. J., … & Brickman, A. M. (2018). The effect of white matter hyperintensities on cognition is mediated by cortical atrophy. Neurobiology of aging, 64, 25-32.

Vonk, J. M., Rizvi, B., Lao, P. J., Budge, M., Manly, J. J., Mayeux, R., & Brickman, A. M. (2018). Letter and Category Fluency Performance Correlates with Distinct Patterns of Cortical Thickness in Older Adults. Cerebral Cortex.

Nasrabady, S. E., Rizvi, B., Goldman, J. E., & Brickman, A. M. (2018). White matter changes in Alzheimer’s disease: a focus on myelin and oligodendrocytes. Acta neuropathologica communications, 6(1), 22.

Stamm, B., Lao, P. J., Rizvi, B., Colon, J., Chesebro, A., Maas, B., Schupf, N., Mayeux, R., Manly, J. J., Brickman, A. M., (2019). Parental history of dementia is associated with increased small vessel cerebrovascular disease. The Journals of Gerontology: Series A.

Yeung, L. K., Hale, C., Rizvi, B., Igwe, K., Sloan, R. P., Honig, L. S., … & Brickman, A. M. (2021). Anterolateral entorhinal cortex volume is associated with memory retention in clinically unimpaired older adults. Neurobiology of Aging, 98, 134-145.

Bertrand, E., Azar, M., Rizvi, B., Brickman, A. M., Huey, E. D., Habeck, C., … & Cosentino, S. (2018). Cortical thickness and metacognition in cognitively diverse older adults. Neuropsychology.

Brickman, A. M., Tosto, G., Gutierrez, J., Andrews, H., Gu, Y., Narkhede, A., Rizvi, B., Guzman, V., Manly, J. J., Vonsattel, J., Schupf, N., Mayeux, R. (2018). An MRI measure of degenerative and cerebrovascular pathology in Alzheimer’s disease. Neurology, 91(15)

Rohaut, B., Doyle, K. W., Reynolds, A. S., Igwe, K., Couch, C., Matory, A., Rizvi, B., … & Park, S. (2018). Deep structural brain lesions associated with consciousness impairment early after hemorrhagic stroke. Scientific reports, 9(1), 4174.

Chesebro, A.G., Melgarejo, J.D., Leendertz, R., Igwe, K.C., Lao, P.J., Laing, K.K., Rizvi, B., Budge, M., Meier, I.B., Calmon, G., Lee, J.H., Maestre, G.E., Brickman, A.M. (2020). White matter hyperintensities mediate the association of nocturnal blood pressure dipping and hypertension with cognition. Neurology, 94(17), e1803-e1810.

Domínguez-Vivero, C., Wu, L., Lee, S., Manoochehri, M., Cines, S., Brickman, A. M., Rizvi, B., … & Cosentino, S. (2020). Structural Brain Changes in Pre-Clinical FTD MAPT Mutation Carriers. Journal of Alzheimer’s Disease, (Preprint), 1-12.

Muhlhofer, W. G., Zak, R., Kamal, T., Rizvi, B., Sands, L. P., Yuan, M., … & Leung, J. M. (2017). Burst-suppression ratio underestimates absolute duration of electroencephalogram suppression compared with visual analysis of intraoperative electroencephalogram. British Journal of Anaesthesia, 118(5), 755-761.

I enjoy doing art in my free time and have followed this passion in art since childhood. More recently, I’ve been creating brain related paintings on my iPad! I also love spending time with close friends and family (including my cat!), enjoying coffee, and going to art museums.

What the lab means to me…
“As an entering member of the Yassa lab, I am excited to get to know everyone more, and so far with my interactions with the members – everyone has been super friendly, approachable, collaborative, and helpful! While it is challenging forming new connections during COVID, I am very much looking forward to connecting with the lab members on a more personal level!“