Cummings CV (Current) click to download
Journal Articles (peer-reviewed)
Anderson, A.J. & B.J. Cummings, “Achieving Informed Consent for Cellular Therapies: A Preclinical Translational Research Perspective on Regulations versus a Dose of Reality” Journal of Medicine, Law, and Ethics (in press) |
Haus, D.L., López-Velázquez, L, Gold, E.M., Cunningham, K.M., Perez, H., Anderson, A.J. & Cummings, B.J (2016). “Transplantation of human neural stem cells restores cognition in an immunodeficient rodent model of traumatic brain injury.” Experimental Neurology. Jul;281:1-16. doi: 10.1016/ j.expneurol.2016.04.008. Epub 2016 Apr 11. PMID 27079998. IF 4.7 |
Koliatsos, VE, L Xu, and B.J. Cummings (2015). “Stem cell therapies for traumatic brain injury” Regenerative Medicine. Nov 6, doi:10.2217/rme.15.62. IF=2.8 |
Chang, J, Phelan, M and Cummings, BJ (2015). “A meta-analysis of efficacy in pre-clinical human stem cell therapies for traumatic brain injury” Experimental Neurology 273, 225-233. IF 4.7 |
Piltti, KM, Avakian, SN, Funes, G, Hu, A, Uchida N., Anderson A.J. and Cummings BJ (2015) “Transplantation dose alters the dynamics of human neural stem cell engraftment, proliferation and migration after spinal cord injury” Stem Cell Research. doi:10.1016/j.scr.2015.07.001. IF 4.8 |
Cummings, BJ* Kiran, P*, Thomas, AM, Shea, LD, Levine, A, Pfaff, S and Anderson, AJ. (2015) “Biomaterial bridges enable regeneration and re-entry of corticospinal tract axons into the caudal spinal cord after SCI: association with recovery of forelimb function” Biomaterials, 65:1-12 doi: 10.1016/j.biomaterials.2015.05.032. Epub 2015 Jun 23. IF=8.9. |
Leyan Xu, Jiwon Ryu, Hakim Hiel, Adarsh Menon, Ayushi Aggarwal, Elizabeth Rha, Vasiliki Mahairaki, Brian J Cummings, and Vassilis E Koliatsos. (2015) Transplantation of human oligodendrocyte progenitor cells in an animal model of diffuse traumatic axonal injury: survival and differentiation Stem Cell Research & Therapy 6(1):93. DOI:10.1186/s13287-015-0087-0 IF=4.6 |
Haus, D., Nguyen, H., Gold, EM, Kamei, N, Perez, H, Moore HD, Anderson, AJ, and Cummings, B.J (2014). “CD133-enriched Xeno-Free human embryonic-derived neural stem cells expand rapidly in culture and do not form teratomas in immunodeficient mice”. Stem Cell Research. http://dx.doi.org/10.1016/j.scr.2014.06.008 IF=4.8 |
Thomas, AM, Seidlits, SK, Goodman, AG, Kukushliev, TV, Hassanic, DM, Cummings, BJ, Anderson, AJ, and Shea, LD (2014) “Sonic hedgehog and neurotrophin-3 increase oligodendrocyte numbers and myelination after spinal cord injury”. Integrative Biology, 6:694-705 DOI: 10.1039/C4IB00009A IF=4.3 |
Nguyen HX, Haus DL, Funes G, Moreno D, Nekanti U, Kamei N, Cummings BJ & Anderson AJ. (2014) “Induction of early neural precursors and derivation of tripotent neural stem cells from human pluripotent stem cells under xeno-free conditions”. J Comp Neurol, DOI: 10.1002/cne.23604 PMID: 24715528. IF=4.0 |
Sontag, C, N. Uchida, B.J. Cummings, and A.J. Anderson. (2014) “Injury to the spinal cord niche alters the engraftment dynamics of human neural stem cells.” (Accepted Sep 16, 2013) Stem Cell Reports, 2:620-632. PMID: 24936450 http://dx.doi.org/10.1016/j.stemcr.2014.03.005 IF 5.4 |
Tuinstra, HM, Goodman, SG, Holland, SJ, Boehler, RM, Zelivyanskaya, ML, Margul, DJ,, Cummings, BJ, Anderson, AJ and LD Shea (2014). “Long-term characterization of axon regeneration and matrix changes using multiple channel bridges for spinal cord regeneration”. Tissue Engineering Part A, 2014 Mar;20(5-6):1027-37. doi: 10.1089/ten.TEA.2013.0111. Epub 2013 Dec 11. PMID: 24168314. IF=4.6 |
Piltti, KM*, Salazar D.L.*, Uchida N., Cummings B.J., and Anderson A.J. (2013b) “Safety of human neural stem cell transplantation in chronic spinal cord injury”. Stem Cells Translational Medicine, 2:961-974. doi: 10.5966/sctm.2013-0064. Epub Nov 4, 2013 PMID: 24191264. IF=3.6 |
Sontag, C, Nguyen, H.X., Kamei, N, Uchida, N., Anderson, A.J.* and Cummings, B.J.* (2013). “Immunosuppressants affect human neural stem cells in vitro, but not in an in vivo model of spinal cord injury” (May 28, 2013) Stem Cells Translational Medicine, Oct;2(10):731-44. doi: 10.5966/sctm.2012-0175. Epub 2013 Aug 27. PMID: 23981724 IF=3.6 |
Gold, E., Su, D., Lopez-Velázquez, L., Haus, D.L., Perez, H., Lacuesta, G., Anderson, A.J.*, & B.J. Cummings* (2013). “Functional Assessment of Long-Term Deficits in Rodent Models of Traumatic Brain Injury” (May 17, 2013) Regenerative Medicine, 8(4):483-516 doi:10.2217/rme.13.41 IF=3.8 |
Piltti, KM*, Salazar D.L.*, Uchida N., Cummings B.J., and Anderson A.J (2013a). “Safety of epicenter versus intact parenchyma as a transplantation site for human neural stem cells for spinal cord injury therapy”. (Feb 14, 2013) Stem Cells Translational Medicine, Mar;2(3):204-216. PMID: 23413374. doi: 10.5966/sctm.2012-0110 IF=3.6 |
Thomas, A, Kubilius, L, Holland, S, Seidlits, S, Boehler, R, Anderson, AJ, Cummings, BJ, and LD Shea (2013). “Channel density and porosity of degradable bridging scaffolds on axon growth after spinal injury.” Biomaterials Mar; 34(9):2213-20. doi: 10.1016/j.biomaterials.2012.12.002. Epub 2013 Jan 2 PMID: 23290832 IF=8.5 |
Uchida, N, K. Chen, K.D. Hansen, J. Dean, J.R. Buser, A. Riddle, D.J. Beardsley, Y. Wan, X. Gong, T. Nguyen, B.J. Cummings, A.J. Anderson, M. Dohse, S.J. Tamaki, S. Matsumoto, L.S. Sherman, C. Kroenke, and S.A. Back (2012). “Human neural stem cells preferentially generate functional myelination in asymptomatic neonates and juvenile mice with severe dysmyelination.” Science Translational Medicine, 4, 155ra136; DOI: 10.1126/scitranslmed.3004371 PMID: 23052293 IF=10.5 |
Tuinstra, HM, Aviles, MO, Shin, S, Holland, SJ, Zelivyanskaya, ML, Fast, AG, Ko, SY, Margul, DJ, Bartels, AK, Boehler, RM, Cummings, BJ, Anderson, AJ and LD Shea (2012). “Multifunctional, multichannel bridges that deliver neurotrophin encoding lentivirus for regeneration following spinal cord injury”. Biomaterials, Feb;33(5):1618-26. PMID: 22130565 IF=8.5 |
Sontag, E.M., Lotzc, G.P., Yang, G., Sontage, C.J., Cummings, B.J., Glabe, C.G., Muchowskic, P.J. and L.M. Thompson (2012). “Detection of Mutant Huntingtin Aggregation Conformers and Modulation of SDS-Soluble Fibrillar Oligomers by Small Molecules” Journal of Huntington Disease 1, 127-140. DOI 10.3233/JHD-2012-129004 IF=na |
Piltti, KM, Haus, DL, Do, E, Perez, H, Anderson, A. J. and BJ Cummings (2011). “Computer-aided 2D and 3D quantification of human stem cell fate from in vitro samples using Volocity high performance image analysis software” Stem Cell Research, doi:10.1016/j.scr.2011.05.005 IF=4.7 |
Anderson, A.J., Haus, D.L.*, Hooshmand, M.J.*, Perez, H.*, Sontag, C.J.*, and B.J. Cummings (2011). Achieving stable human stem cell engraftment and survival in the CNS: Is the future of regenerative medicine immunodeficient? Regenerative Medicine, 6(3), 367-406. doi:10.2217 PMID: 21548741 IF=3.8 |
Salazar, D. L., N. Uchida, F. Hammers, A.J. Anderson*, and B.J. Cummings* (2010). “Human neural stem cells differentiate and promote locomotor recovery in an early chronic spinal cord injury NOD-scid mouse model” Public Library of Science ONE. Aug 18;5 (8) 1-15 e12272. doi:10.1371/journal.pone.0012272 PMID: 20806064 IF=4.2 |
Luchetti S, Beck KD, Galvan MD, Silva R, Cummings BJ, Anderson AJ. (2010). “Comparison of immunopathology and locomotor recovery in C57BL/6, BUB/BnJ and NOD-scid mice after contusion spinal cord injury” J Neurotrauma Feb 27(2): 411-421. PMID: 19831737. IF=4.8 |
Nasonkin, I., V. Mahairaki, L.Xu, G.Hatfield, B.J.Cummings, C. Eberhart, D.Ryugo, D. Maric, E.Bar and V.E. Koliatsos (2009). “Long-Term, Stable Differentiation Of Human Embryonic Stem Cell-Derived Neural Precursors Grafted Into The Adult Mammalian Neostriatum.” Stem Cells Oct;27(10):2414-2426. PMID: 19609935 IF=8.4 |
Yang, Y, L. De Laporte, M.L. Zelivyanskaya, K.J. Whittlesey, A.J. Anderson, B.J. Cummings, and L.D. Shea (2009). “Multiple Channel Bridges for Spinal Cord Injury: Cellular Characterization of Host Response.” Tissue Engineering: Part A, Nov;15(11) 3283-3295. PMID: 19382871 IF=4.6 |
Hooshmand, M. J., C. J. Sontag, N. Uchida, S. J. Tamaki, A. J. Anderson*, and B.J. Cummings* (2009). “Analysis of host-mediated repair mechanisms after human CNS-stem cell transplantation for spinal cord injury: correlation of engraftment with recovery.” Public Library of Science (PLoS) ONE, Jun 11;4(6):e5871. PMID: 19517014 IF=4.2 |
De Laporte, L, Y. Yang, M.L. Zelivyanskaya, B.J. Cummings, A.J. Anderson, L.D. Shea (2008) “Plasmid releasing multiple channel bridges for transgene expression after spinal cord injury” Molecular Therapy Feb;17(2):318-326. PMID: 19050701 IF=6.5 |
Cummings, B.J., C. Engesser-Cesar, G. Cadena, and A.J. Anderson (2007). “Adaptation of a ladder beam walking task to assess locomotor recovery in mice following spinal cord injury.” Behavioral Brain Research, Feb 27;177, 232-241. PMID: 17197044 IF=3.7 |
Cummings, B.J., N. Uchida, S.J. Tamaki, and A.J. Anderson (2006). Human neural stem cell differentiation following transplantation into spinal cord injured mice: Association with recovery of locomotor function. Neurological Research, 28(5) 474-481. PMID: 16808875 IF=1.3 |
Chubb, C., Y. Inagaki, P.C.Y. Sheu, B.J. Cummings, A.J. Wasserman, E. Head, and C.W. Cotman (2006). “BioVision: An application for the automated image analysis of histological sections.” Neurobiology of Aging, 27(10): 1462-1476. PMID: 16271803 IF=6.1 |
Luchetti, S., F di Michele, E. Romeo, L. Brusa, G Bernardi, BJ Cummings, P. Longone (2006). “Comparative non-radioactive RT-PCR assay: An approach to study the neurosteroids biosynthetic pathway in humans.” J Neurosci Methods. 153(2):290-298. PMID: 16378642 IF=2.5 |
Cummings, B.J., N. Uchida, S.J. Tamaki, D.L. Salazar, M. Hooshmand, R. Summers, F.H. Gage, and A.J. Anderson (2005) “Human Neural Stem Cells Differentiate and Promote Locomotor Recovery in Spinal Cord-Injured Mice.” Proceedings of the National Academy of Sciences, Sep 27;102(39):14069-14074. PMID: 16172374 IF=10.6 |
Chubb, C., Y. Inagaki, C.W. Cotman, B.J. Cummings, and P.C.Y. Sheu (2004). Semantic Biological Image Management and Analysis. International Journal on Artificial Intelligence Tools, 13(4) 881-896. IF=0.45 |
Zhao, M., D.H. Cribbs, A.J. Anderson, B.J. Cummings, J.H. Su, A.J. Wasserman and C.W. Cotman (2003). “The induction of the TNF-alpha death domain signaling pathway in Alzheimer’s disease brain.” Neurochemical Research, 28(2): 307-318. IF=2.4 |
Cummings, B.J., A.J. Mason, R.C. Kim, P.C.Y. Sheu, and A.J. Anderson (2002). “Optimization of techniques for the detection and quantification of Alzheimer’s-related neuropathology with digital imaging.” Neurobiology of Aging, 23: 161-170. IF=6.1 |
Anderson, A.J., W.W Ruehl, L.K Fleischmann, K. Stenstrom, T.L. Entriken, and B.J. Cummings (2000). “DNA damage and apoptosis in the aged canine brain: Relationship to Aß deposition in the absence of neuritic pathology. Prog. Neuro-Psychopharmacol & Biol Psychiat 24: 787-799. IF=3.6 |
Su, J.H, B.J. Cummings, and C.W. Cotman (1998). “Plaque biogenesis in brain aging and Alzheimer’s disease II. Progressive transformation and developmental sequence of dystrophic neurites.” Acta Neuropathologica. 96: 463-471. IF=9.7 |
Cummings, B.J. (1997) Plaques and tangles: Searching for primary events in a forest of data. Neurobiology of Aging 18, 358-362. IF=6.1 |
Head, E., H. Callahan, B.J. Cummings, C.W. Cotman, W.W. Ruehl, B.A. Muggenburg, and N.W. Milgram (1997). “Open field activity and human interaction as a function of age and breed in dogs.” Physiology and Behavior, 62(5), 963-971. IF=3.3 |
Satou, T., B.J. Cummings, E Head, K.A. Nielson, F. Hahn, N.W. Milgram, P. Velazquez, D.H. Cribbs, A.J. Tenner, and C.W. Cotman (1997). “Progression of ß-amyloid deposition within the frontal cortex of the dog.” Brain Research, 774: 35-43. IF=2.9 |
Cummings, B.J., C.J. Pike, R. Shankle, and C.W. Cotman (1996). “ß-amyloid deposition and other measures of neuropathology predict cognitive status in Alzheimer’s disease.” Neurobiology of Aging, 17, 921-933. IF=6.1 |
Su, J. H., B.J. Cummings, C.W. Cotman (1996). Plaque biogenesis in brain aging and Alzheimers disease. I. Progressive changes in phosphorylation states of paired helical filaments and neurofilaments. Brain Research, 739:79-87. IF=3.0 |
Cummings, B.J., T. Satou, E. Head, N.W. Milgram, G.M. Cole, M.J. Savage, M.B. Podlisny, D.J. Selkoe, R. Siman, B.D. Greenberg, and C.W. Cotman (1996). “Diffuse plaques contain C-terminal Aß42 and not Aß40: Evidence from cats and dogs.” Neurobiology of Aging, 17, 653-659. IF=6.1 |
Cotman, C.W., A.J. Tenner, and B.J. Cummings (1996). ß-amyloid converts an acute phase injury response to chronic injury responses.” Neurobiology of Aging, 17, 723-731. IF=6.1 |
Cummings, B.J., E. Head, A. Afagh, N.W. Milgram and C.W. Cotman (1996). “ß-amyloid accumulation correlates with cognitive impairment in the aged canine.” Neurobiology of Learning and Memory, 66 (1), 11-23. IF=3.9 |
Nielson, K.A., B.J. Cummings, and C.W. Cotman (1996). “Constructional apraxia in Alzheimer’s disease correlates with neuritic neuropathology in occipital cortex.” Brain Research, 741, 284-293. PMID: 9001734 IF=3.0 |
Cummings, B.J., E. Head, W. Ruehl, N.W. Milgram and C.W. Cotman (1996). “The canine as an animal model of human aging and dementia.” Neurobiology of Aging, 17, 259-268. IF=6.1 |
Head, E., R. Mehta, J. Hartley, W. Ruehl, B.J. Cummings, C.W. Cotman, C. Reid and N.W. Milgram (1995). “Spatial learning and memory in young and aged dogs.” Behavioral Neuroscience, 109, 851-858. IF=3.0 |
Cummings, B.J.*, A. Afagh*, D. Cribbs, C.W. Cotman and A.J. Tenner (1996). “Localization and cell association of C1q in Alzheimer’s disease brain.” Experimental Neurology, 138, 22-32. IF=4.5 |
Satou, T., B.J. Cummings, and C.W. Cotman (1995). “Immunoreactivity for Bcl-2 protein within neurons in the Alzheimer’s disease brain increases with disease severity” Brain Research, 697, 35-43. IF=3.0 |
Ruehl, W.W., D. Bruyette, A. DePaoli, C.W. Cotman, E. Head, N.W. Milgram, and B.J Cummings (1995). “Canine cognitive dysfunction as a model for human age related cognitive decline, dementia and Alzheimer’s disease: Clinical presentation, cognitive testing, pathology and response to l-deprenyl therapy.” Progress in Brain Research, 106, 217-225. IF=3.7 |
Cummings, B.J. and C.W. Cotman (1995). “Image analysis of ß-amyloid “load” in Alzheimer’s disease and relation to dementia severity.” The Lancet, 346, 1524-15-28. IF=36.4 |
Pike, C.J, B.J. Cummings, and C.W. Cotman (1995). “Early association of reactive astrocytes with senile plaques in Alzheimer’s disease.” Experimental Neurology 132(2), 172-179. IF=4.5 |
DeFigueiredo, R., B.J. Cummings, P. Mundkur and C.W. Cotman (1995). “Color image analysis in neuroanatomical research: Application to senile plaque subtype quantification in Alzheimer’s disease.” Neurobiology of Aging 16(2), 211-223. IF=6.1 |
Su, J.H., A.J. Anderson, B.J. Cummings, and C.W. Cotman (1994). “Immunocytochemical evidence for apoptosis in Alzheimer’s disease.” NeuroReport 5(18): 2529-2533. IF=1.9 |
Pike, C.J., B.J. Cummings, R. Monzavi and C.W. Cotman (1994). “ß-Amyloid-induced changes in cultured astrocytes parallel reactive astrocytosis associated with senile plaques in Alzheimer’s disease.” Neuroscience 63(2): 517-531. IF=3.4 |
Su, J.H., B.J. Cummings, and C.W. Cotman (1994). “Early phosphorylation of tau in Alzheimer’s disease occurs at Ser-202 and is preferentially within neurites.” NeuroReport 5(7): 2358-2362. IF=1.9 |
Smyth, M, J.P. Kesslak, B.J. Cummings, and C.W. Cotman (1994). “Analysis of brain injury following intrahippocampal administration of ß-amyloid in streptozotocin-treated rats.” Neurobiology of Aging 15:153-159. IF=6.1 |
Su, J.H., B.J. Cummings, and C.W. Cotman (1994). “Subpopulations of dystrophic neurites in Alzheimer’s disease exhibit distinct immunocytochemical and argentophilic characteristics.” Brain Research 637: 37-44 IF=3.0 |
Anderson, A.J., B.J. Cummings, and C.W. Cotman (1994). “Jun and Fos immunoreactivity in Alzheimer’s brain and induction by ß-amyloid in cultured neurons.” Experimental Neurology 125: 286-295. IF=4.5 |
Cummings, B.J., J.H. Su and C.W. Cotman (1993). “Neuritic involvement within bFGF immunopositive plaques of Alzheimer’s disease.” Experimental Neurology 124:315-325. IF=4.5 |
Su, J.H., B.J. Cummings, and C.W. Cotman (1993). “Identification and distribution of axonal dystrophic neurites in Alzheimer’s disease.” Brain Research 625:228-237. IF=3.0 |
Russell, M., B.J. Cummings, B. Profitt, C. Wysocki, A. Gilbert and C.W. Cotman (1993). “Lifespan changes in the verbal categorization of odors.” Journal of Gerontology 48: 49-53. IF=4.6 |
Cummings, B.J., J.H. Su, C.W. Cotman, R. White and M. Russell (1993). “ß-amyloid accumulation in aged canine brain: A model of plaque formation in Alzheimer’s disease.” Neurobiology of Aging 14:547-560. IF=6.1 |
Su, J.H., B.J. Cummings and C.W. Cotman (1992). “Localization of heparan sulfate glycosaminoglycan and proteoglycan core protein in aged brain and Alzheimer’s disease.” Neuroscience 51: 801-814. IF=3.4 |
Pike, C.J., B.J. Cummings and C.W. Cotman (1992). “ß-amyloid induces neuritic dystrophy in vitro: Similarities with Alzheimer pathology.” NeuroReport 3: 769-772. IF=1.9 |
Cummings, B.J., G.J. Yee and C.W. Cotman (1992). “bFGF promotes entorhinal layer II cell survival after perforant path axotomy.” Brain Research 591: 271-276. IF=3.0 |
Kammesheidt, A., F.M. Boyce, A.F. Spanoyannis, B.J. Cummings, M. Ortegón, C. Cotman, J.L. Vaught and R.L. Neve (1992). “Amyloid deposition and neuronal pathology in transgenic mice expressing the carboxyterminal fragment of the Alzheimer amyloid precursor in the brain.” Proceedings of the National Academy of Science 89: 10857-10861. IF=10.6 |
Bridges, R.J., C.G. Hatalski, S.N. Shim, B.J. Cummings, V. Vijayan, A. Kundi and C.W. Cotman (1992). “Gliotoxic actions of excitatory amino acids.” Neuropharmacology 31: 899-907. IF=4.4 |
Cummings, B.J., J.H. Su, J.W. Geddes, W. Van Nostrand, S. Wagner, D. Cunningham and C.W. Cotman (1992). “Aggregation of the amyloid precursor protein (APP) within degenerating neurons and dystrophic neurites in Alzheimer’s Disease.” Neuroscience 48: 763-777. IF=3.4 |
Gómez-Pinilla, F., B.J. Cummings and C.W. Cotman (1990). “Induction of basic fibroblast growth factor in Alzheimer’s disease pathology.” NeuroReport 1: 211-214. IF=1.9 |