We are excited to share that our paper which examines DNA methylation in relation to glyphosate exposure has been published in Environmental Health Perspectives! This was a labor of love, funded by the California Breast Cancer Research Program and powered by a talented and multi-disciplinary group of scientists; generous and dedicated study participants; and passionate and devoted patient advocates.
Glyphosate, the active ingredient in Roundup, is the most commonly used pesticide in the world and is purported to have a variety of health effects. In 2015 the IARC – International Agency for Research on Cancer/World Health Organization classified glyphosate as “probably carcinogenic to humans.” We conducted the first-ever epigenome-wide association study to identify blood DNA methylation markers for glyphosate exposure. We also found that urinary levels of its metabolite, AMPA, were associated with DNA methylation of Estrogen Receptor 1 (ESR1) and with greater epigenetic age acceleration. The open-access full-text article is here: https://ehp.niehs.nih.gov/doi/10.1289/EHP10174