Biobanking is fundamental to modern biomedical research; biospecimens are the necessary fuel that permit study of disease effects on human tissues. Dr. Yong has long experience in biobanking beginning as a neuropathology fellow procuring brain samples for the UCLA Alzheimer Disease Research Center. While at Cedars-Sinai Medical Center, he procured autopsy brains for the California NeuroAIDS Tissue Network and banked brain cancer samples for the brain tumor program. He was the Director of the Brain Tumor Translational Resource and Lead investigator for the biospecimen core for the NIH-funded UCLA Brain Cancer SPORE. Currently, he is a neuropathologist supporting the National Neurological AIDS Brain Bank, the UC Irvine Alzheimer Disease Research Center and Alzheimer’s Biomarker Consortium-Down Syndrome. Many talented and successful trainees have contributed to the biobanking work and to publishing on biobanking issues and methods.
Procurement, Storage, and Use of Blood in Biobanks.Perry JN, Jasim A, Hojat A, Yong WH.Methods Mol Biol. 2019;1897:89-97. doi: 10.1007/978-1-4939-8935-5_9.
Procurement and Storage of Surgical Biospecimens.Hojat A, Wei B, Olson MG, Mao Q, Yong WH.Methods Mol Biol. 2019;1897:65-76. doi: 10.1007/978-1-4939-8935-5_7.
An Introduction to Starting a Biobank.Harati MD, Williams RR, Movassaghi M, Hojat A, Lucey GM, Yong WH.Methods Mol Biol. 2019;1897:7-16. doi: 10.1007/978-1-4939-8935-5_2.
Orientation and Training of New Biobank Personnel.Williams RR, Gupta D, Yong WH.Methods Mol Biol. 2019;1897:51-63. doi: 10.1007/978-1-4939-8935-5_6.
Biobanking of Cerebrospinal Fluid.Tashjian RS, Vinters HV, Yong WH.Methods Mol Biol. 2019;1897:107-114. doi: 10.1007/978-1-4939-8935-5_11.
Domestic and International Shipping of Biospecimens.Gordy D, Tashjian RS, Lee H, Movassaghi M, Yong WH.Methods Mol Biol. 2019;1897:433-443. doi: 10.1007/978-1-4939-8935-5_35
Sustainability in Biobanking.Abdaljaleel M, Singer EJ, Yong WH.Methods Mol Biol. 2019;1897:1-6. doi: 10.1007/978-1-4939-8935-5_1.
A practical approach to clinical and research biobanking.Yong WH, Dry SM, Shabihkhani M.Methods Mol Biol. 2014;1180:137-62. doi: 10.1007/978-1-4939-1050-2_8.
The procurement, storage, and quality assurance of frozen blood and tissue biospecimens in pathology, biorepository, and biobank settings.Shabihkhani M, Lucey GM, Wei B, Mareninov S, Lou JJ, Vinters HV, Singer EJ, Cloughesy TF, Yong WH. Clin Biochem. 2014 Mar;47(4-5):258-66. doi: 10.1016/j.clinbiochem.2014.01.002. Epub 2014 Jan 12.
A review of room temperature storage of biospecimen tissue and nucleic acids for anatomic pathology laboratories and biorepositories.Lou JJ, Mirsadraei L, Sanchez DE, Wilson RW, Shabihkhani M, Lucey GM, Wei B, Singer EJ, Mareninov S, Yong WH.Clin Biochem. 2014 Mar;47(4-5):267-73. doi: 10.1016/j.clinbiochem.2013.12.011. Epub 2013 Dec 18.
Lyophilized brain tumor specimens can be used for histologic, nucleic acid, and protein analyses after 1 year of room temperature storage.Mareninov S, De Jesus J, Sanchez DE, Kay AB, Wilson RW, Babic I, Chen W, Telesca D, Lou JJ, Mirsadraei L, Gardner TP, Khanlou N, Vinters HV, Shafa BB, Lai A, Liau LM, Mischel PS, Cloughesy TF, Yong WH.J Neurooncol. 2013 Jul;113(3):365-73. doi: 10.1007/s11060-013-1135-1. Epub 2013 May 3.