We provide neuropathology support to the National Neurological AIDS Brain Bank and collaborate with colleagues at UCLA and UC Irvine on evaluating brains to study the neuropathology of AIDS and COVID-19.
Neuropathology of COVID-19 (neuro-COVID): clinicopathological update. Lou JJ, Movassaghi M, Gordy D, Olson MG, Zhang T, Khurana MS, Chen Z, Perez-Rosendahl M, Thammachantha S, Singer EJ, Magaki SD, Vinters HV, Yong WH. Free Neuropathol. 2021 Jan 18;2:2. doi: 10.17879/freeneuropathology-2021-2993.
Microglia Do Not Restrict SARS-CoV-2 Replication following Infection of the Central Nervous System of K18-Human ACE2 Transgenic Mice. Olivarria GM, Cheng Y, Furman S, Pachow C, Hohsfield LA, Smith-Geater C, Miramontes R, Wu J, Burns MS, Tsourmas KI, Stocksdale J, Manlapaz C, Yong WH, Teijaro J, Edwards R, Green KN, Thompson LM, Lane TE. J Virol. 2022 Feb 23;96(4):e0196921. doi: 10.1128/jvi.01969-21. Epub 2021 Dec 22. PMID: 34935438; PMCID: PMC8865461.
Neuropathologic Findings in Elderly HIV-Positive Individuals. Magaki SD, Vinters HV, Williams CK, Mareninov S, Khanlou N, Said J, Nemanim N, Gonzalez J, Morales JG, Singer EJ, Yong WH. J Neuropathol Exp Neurol. 2022 Jun 20;81(7):565-576. doi: 10.1093/jnen/nlac040. PMID: 35656871; PMCID: PMC9425852.
HIV, pathology and epigenetic age acceleration in different human tissues. Horvath S, Lin DTS, Kobor MS, Zoller JA, Said JW, Morgello S, Singer E, Yong WH, Jamieson BD, Levine AJ. Geroscience. 2022 Jun;44(3):1609-1620. doi: 10.1007/s11357-022-00560-0. Epub 2022 Apr 11. PMID: 35411474; PMCID: PMC9213580.
HIV DNA Is Frequently Present within Pathologic Tissues Evaluated at Autopsy from Combined Antiretroviral Therapy-Treated Patients with Undetectable Viral Loads. Lamers SL, Rose R, Maidji E, Agsalda-Garcia M, Nolan DJ, Fogel GB, Salemi M, Garcia DL, Bracci P, Yong W, Commins D, Said J, Khanlou N, Hinkin CH, Sueiras MV, Mathisen G, Donovan S, Shiramizu B, Stoddart CA, McGrath MS, Singer EJ.J Virol. 2016 Sep 29;90(20):8968-83. doi: 10.1128/JVI.00674-16. Print 2016 Oct 15.
HIV stroke risk: evidence and implications. Singer EJ, Valdes-Sueiras M, Commins DL, Yong W, Carlson M. Ther Adv Chronic Dis. 2013 Mar;4(2):61-70. doi: 10.1177/2040622312471840.
Optimal conditions for synthesizing complementary DNA in the HIV-1 endogenous reverse transcriptase reaction. Yong WH, Wyman S, Levy JA. AIDS. 1990 Mar;4(3):199-206. doi: 10.1097/00002030-199003000-00004. PMID: 1693515.