Our research interests focus on
1) Developing advanced imaging and Non-invasive detection methods:
- 2-photon excitation, SHG & THG imaging
- Deep tissue Imaging
- Fluorescence Lifetime Imaging Microscopy (FLIM)
- Bioluminescence Imaging
2) Dynamic imaging of single molecular detection
- Raster image correlation spectroscopy (RICS) method
- the Number and Molecular Brightness (N&B) analysis
3) Biological Applications
- The research thrusts in my lab are focused on cell migration/invasion involving mechanical cues that activate mitochondria using noninvasive and label free imaging of metabolic signatures with a focus on using tumor organoids to monitor leader cells.
- My research is also focused on understanding the biophysical mechanisms that occur, at the molecular scale, when cells undergo cellular stress causing changes in physical parameters that regulate the formation of cellular condensates.
- We are developing a multiplexed analysis, to understand cellular organization and cancer cell metastasis.
- PAST and CURRENT FUNDING SOURCES:
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