Our TiNS review “Neurocognitive aging and the hippocampus across species” is now online. Here are some of the trends we discuss in the article: The role of neurogenesis in the dentate gyrus in the context of neurocognitive aging has been recently revisited, given data suggesting that neurogenesis continues into older adulthood. The lateral entorhinal and…
Our recent paper in Learning & Memory, which tests a key prediction of our Competitive Trace Theory, was covered in a UC Irvine press release today! Here’s the write-up: UC Irvine neurobiologists Zachariah Reagh and Michael Yassa have found that while repetition enhances the factual content of memories, it can reduce the amount of detail…
New paper by Zach Reagh in Learning and Memory. Here he is with the paper pony! Reagh, Z.M. & Yassa, M.A. (2014). Repetition strengthens target recognition but impairs similar lure discrimination: evidence for trace competition. Learning & Memory DOI doi/10.1101/lm.034546.114. Abstract: Most theories of memory assume that representations are strengthened with repetition. We recently proposed…
New paper by graduate student Jared Roberts. Here he is with the paper pony! Roberts J.M., Ly, M., Murray, E., Yassa, M.A. (2014) Temporal discrimination deficits as a function of lag interference in older adults. Hippocampus DOI:10.1002/hipo.22303 Abstract A vital component of episodic memory is the ability to determine the temporal order of remembered events. Although it has been…
New paper by graduate student Stephanie Leal. Here she is holding the paper pony! Leal, S.L., Tighe, S.K., Jones, C.K., Yassa, M.A. (2014) Pattern separation of emotional information in hippocampal dentate and CA3.Hippocampus DOI:10.1002/hipo.22298. Abstract: Emotional arousal, mediated by the amygdala, is known to modulate episodic memories stored by the hippocampus, a region involved in pattern separation (the…
Our News and Views piece covering the fantastic work by Khan and colleagues in Nature Neuroscience is out in the current issue. Abstract: New findings in preclinical Alzheimer’s disease patients and mouse models of the disease suggest that it is the lateral, rather than the medial, entorhinal cortex that is most susceptible to tau pathology early…
Our latest work has just been published in Nature Neuroscience. Advance online publication here. Congratulations to Daniel Borota, Liz Murray, Allen Chang, Gizem Keceli, Maria Ly, Joe Watabe and John Toscano for their hard work and collaborative spirit that made this work possible. Read more here….
Our article on Competitive Trace Theory has apparently been a hit and is gaining traction at least with the online community. Here are some of the recent statistics reported by Altmetric. We’re in the top 5% of all articles ever tracked by Altmetric! The article has also received some attention from Tweeters and bloggers. Of…
A new paper from our lab just went in press! Reagh, Z.M., Roberts, J.M., Ly, M., DiProspero, N., Murray, E., Yassa, M.A. (2013) Spatial discrimination deficits as a function of mnemonic interference in aged adults with and without memory impairment. Hippocampus DOI: 10.1002/hipo.22224 Congratulations to first author Zach Reagh! Abstract: It is well established that aging is…