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2019

74. Transplantation of stem cells from umbilical cord blood as therapy for type 1 diabetes. Rachel Stiner, Michael Alexander, Guangyang Liu, Wenbin Liao, Yongjun Liu, Jingxia Yu, Egest Pone, Weian Zhao, Jonathan Lakey. (In press) Cell and Tissue research. (2019)

73. mRNA rescues neonatal acidemia while mice report no aftereffectsJan Zimak, Yonglei Shang, Weian Zhao. EBioMedicine. (2019); Vol 45, 519-528.

72. Combinatorial targeting of cancer bone metastasis using mRNA engineered stem cells. Aude I. Segaliny, Jason L. Cheng, Henry P. Farhoodi, Michael Toledano, Chih Chun Yu, Beatrice Tierrai, Leanne Hildebrand, Linan Liu, Michael J. Liao, Jaedu Chog, Dongxu Liuh, Lizhi Sunh, Gultekin Gulseng, Min-Ying Sug, Robert L. Sahi, Weian Zhao. EBioMedicine.
Featured in UCI NewsUCI team pioneers cancer treatment that targets bone metastases while sparing bone
Featured in the LA Times: UCI team develops noninvasive bone cancer treatment using stem cells

Fig. 1

71. Stem Cell-Derived Exosomes as Nanotherapeutics for Autoimmune and Neurodegenerative Disorders . Milad Riazifar, Reza Mohammadi, Egest Pone, Ashish Yeri, Cecilia Lässer, Aude Segaliny, Laura McIntyre, Ganesh Shelke, Elizabeth Hutchins, Ashley Hamamoto, Erika Calle, Rossella Crescitelli, Wenbin Liao, Victor Pham, Yanan Yin, Jayapriya Jayaraman, Jonathan Lakey, Craig Walsh, Kendall Van Keuren-Jensen, Jan Lotvall, Weian Zhao*. ACS Nano. (2019); Vol. 13, Issue 6, 6670-6688.
Featured in UCI News Nanotechnology treatment shows promise against multiple sclerosis

70. Fluorescence lifetime detection with particle counting devices. Per Niklas Hedde, Tim Abram, Tam Vu, Weian Zhao, Enrico Gratton*.  Biomedical Optics Express. (2019); Vol. 10, Issue 3: 1223-1233.

69. An ultrasensitive test for profiling circulating tumor DNA using integrated comprehensive droplet digital detection . Chen-Yin Ou, Tam Vu,Jonathan T. Grunwald, Michael Toledano, Jan Zimak, Melody Toosky, Byron Shen, Jason A. Zell, Enrico Gratton, Timothy J. Abram*, Weian Zhao*. Lab on Chip. (2019); Vol. 19: 993-1005.


2018

      1. A simple DNAzyme-based fluorescent assay for Klebsiella pneumoniae. M. Monsur Ali*, Anatoly Slepenkin, Ellena Peterson, Weian Zhao*. ChemBioChem. (2018); Vol. 20, Issue 7: 906-910.
      1. Functional TCR T cell screening using single-cell droplet microfluidics. Aude I. Segaliny, Guideng Li, Lingshun Kong, Ci Ren, Xiaoming Chen, Jessica K. Wang, David Baltimore, Guikai Wu, Weian Zhao*. Lab on Chip. (2018); Vol. <span class=”list__item-data” aria-label=”Lab Chip, 2018,18, 3733-3749″>18: 3733-3749.

Featured in UCI News New immunotherapy technique can specifically target tumor cells, UCI study reports
Featured as  Editor’s Choice in Science Translational Medicine:  10,368 first dates: Microfluidic T cell matchmaking

      1. Enhanced Therapeutic Effects of MSC-derived Exosomes with an Injectable Hydrogel for Hindlimb Ischemia Treatment. Kaiyue Zhang, Xiangnan Zhao, Xiaoniao Chen, Yongzhen Wei, Wei Du, Yuebing Wang, Linan Liu, Weian Zhao, Zhibo Han, Deling Kong, Qiang Zhao, Zhikun Guo, Zhongchao Han, Na Liu, Fengxia Ma, and Zongjin Li. Applied Materials and Interfaces. (2018); Vol. 10, Issue 36: 30081-30091.

      1. Targeting Biophysical Cues: A Niche Approach to Study, Diagnose, and Treat Cancer. Shirley Zhang, Linan Liu, and Weian Zhao*Trends in Cancer. (2018); Vol. 4, Issue 4: 268-271.

Published in a special issue on “Physical Forces in Cancer”.
News: Americans for Cures


2017

      1. Emerging Microtechnologies and Automated Systems for Rapid Bacterial Identification and Antibiotic Susceptibility Testing. Yiyan Li, Xing Yang, Weian ZhaoSLAS Technology. (2017); Vol. 22: Issue 6. 

Recognized as a top 10 paper by SLAS Technology in 2017.

      1. Mechano-Responsive Stem Cells to Target Cancer Metastases Through Biophysical Cues. Linan Liu, Shirley X. Zhang, Wenbin Liao, Henry P. Farhoodi, Chi W. Wong, Claire C. Chen, Aude I. Ségaliny, Jenu V. Chacko, Lily P. Nguyen, Mengrou Lu, George Polovin, Egest J. Pone, Timothy L. Downing, Devon A. Lawson, Michelle A. Digman, Weian Zhao*Science Translational Medicine. (2017); Vol 9: Issue 400.

        Featured by UCI News
        Featured in The ScientistStem Cells Seek Out Tumors Based on Stiffness
        Featured in Genetic Engineering and Biotechnology NewsCell-Based Therapies Soften Up Cancer by Targeting Tumor Stiffness.

      1. A Mathematical Model of Mechanotransduction Reveals How Mechanical Memory Regulates Mesenchymal Stem Cell Fate Decisions. Tao Peng, Linan Liu, Adam L MacLean, Chi Wut Wong, Weian Zhao* and Qing Nie*. BMC Systems Biology. (2017); Vol. 11, Issue 55.

      1. Developing Best-Practice Models for the Therapeutic Use of Extracellular Vesicles. Kenneth W. Witwer, Agnes T. Reiner, Bas W. M. van Balkom, Joel de Beer, Chaya Brodie, Randolph L. Corteling, Hernando A. del Portillo, Susanne Gabrielsson, Mario Gimona, Ahmed G. Ibrahim, Dominique de Kleijn, Charles P. Lai, Thomas Lener, Jan Lötvall, Ilona G. Reischl, Milad Riazifar, Carlos Salomon, Hidetoshi Tahara, Wei Seong Toh, Marca Wauben, Vicky K. Yang, Yijun Yang, Ronne Wee Yeh Yeo, Hang Yin, Bernd Giebel, Eva Rohde and Sai Kiang Lim. Stem cells translational medicine. (2017); Vol. 6: 1730–1739.

2016

      1. The International Society for Extracellular Vesicles launches the first massive open online course on extracellular vesicles. Lässer C, Théry C, Buzás EI, Mathivanan S, Weian Zhao, Gho YS, Lötvall J. Journal of Extracellular Vesicles. (2016); Vol. 5: 34299.

      1. Tetrandrine identified in a small molecule screen to activate mesenchymal stem cells for enhanced immunomodulation. Zijiang Yang, John Concannon, Kelvin Ng, Kathleen Seyb, Luke Mortensen, Sudhir Ranganath, Fangqi Gu, Oren Levy, Zhixiang Tong, Keir Martyn, Weian Zhao, Charles Lin, Marcie Glicksman and Jeffrey Karp. Scientific Reports. (2016); Vol. 6: 30263.

      1. Elucidation of exosome migration across the blood-brain barrier model in vitroClaire C. Chen, Linan Liu, Fengxia Ma, Chi W. Wong, Xuning E. Guo, Jenu V. Chacko, Henry P. Farhoodi, Shirley X. Zhang, Jan Zimak, Aude Ségaliny, Milad Riazifar, Victor Pham, Michelle A. Digman, Egest J. Pone and Weian Zhao*Cellular and Molecular Bioengineering. (2016); Vol. 9, Issue 4: 509-529.

58. EV BBB

      1. Stem cell extracellular vesicles: extended messages of regenerationMilad Riazifar, Egest J. Pone, Jan Lötvall, and Weian Zhao*Annual Review of Pharmacology and Toxicology. (2016); Vol. 57: 125-154. 
        57. EV review

2015

      1. Mesenchymal stem cells engineered to express selectin ligands and IL-10 exert enhanced therapeutic efficacy in murine experimental autoimmune encephalomyelitis. Wenbin Liao, Victor Pham, Linan Liu, Milad Riazifar, Egest J. Pone, Shirley X. Zhang, Fengxia Ma, Mengrou Lu, Craig M. Walsh, and Weian Zhao*. Biomaterials. (2015); Vol. 77: 87-97.Mesenchymal stem cells engineered to express selectin ligands and IL-10 exert enhanced therapeutic efficacy in murine experimental autoimmune encephalomyelitis

      1. Floating droplet array: an ultrahigh-throughput device for droplet trapping, real-time analysis and recoveryLouai Labanieh, Thi Nguyen, Weian Zhao*, and Dong-Ku Kang*. Micromachines. (2015); Vol. 6, Issue 10: 1469-1482.

        Screenshot 2015-11-03 11.21.55

      1. Digital Quantification of miRNAs directly in plasma using Integrated Comprehensive Droplet Digital Detection. Kaixiang Zhang, Dong-Ku Kang, M. Monsur Ali, Linan Liu, Louai Labanieh, Mengrou Lu, Hamidreza Riazifar, Thi N. Nguyen, Jason A. Zell, Michelle A. Digman, Enrico Gratton, Jinghong Li*, and Weian Zhao*. Lab on a Chip. (2015); <span class=”list__item-data” aria-label=”Lab Chip, 2015,15, 4217-4226″>Vol. 15: 4217-4226.

        Lab chip1

      1. Exogenous marker-engineered mesenchymal stem cells detect cancer and metastases in a simple blood assay. Linan Liu, Shirley X Zhang, Rangoli Aeran, Wenbin Liao, Mengrou Lu, George Polovin, Egest J Pone, Weian Zhao*. Stem Cell Research & Therapy. (2015); Vol. 6, Issue 181.MSC for cancer detection
      1. Construct real-time, wash-free, and reiterative sensors for cell surface proteins using binding-induced dynamic DNA assembly. Yanan Tang, Zhixin Wang, Junbo Chen, Linan Liu, Weian Zhao, X. Chris Le, and Feng Li. Chemical Sciences. (2015); <span class=”list__item-data” aria-label=”Chem. Sci., 2015,6, 5729-5733″>Vol. 6: 5729-5733.

        Screenshot 2015-08-11 11.33.54

      1. Facile supermolecular aptamer inhibitors of L-selectin. Elizabeth K Chang, Mark A Eckert, M. Monsur Ali, Hamidreza Riazifar, Egest J. Pone, Linan Liu, and Weian Zhao*PLoS One. (2015); Vol. 10, Issue 3: e0123034.Figure 1
      1. Nucleic acid aptamers in cancer research, diagnosis and therapy. Haitao Ma, Jinping Liu, M. Monsur Ali, M. Arif Iftakher Mahmood, Louai Labanieh, Mengrou Lu, Samir M Iqbal, Qun Zhang, Weian Zhao* and Yuan Wan*. Chemical Society Reviews. (2015); Vol <span class=”list__item-data” aria-label=”Chem. Soc. Rev., 2015,44, 1240-1256″>44: 1240-1256. 50 Nucleic acid aptamers in cancer research diagnosis and therapy Graphic abstract

2014

      1. Rapid detection of single bacteria in unprocessed blood using Integrated Comprehensive Droplet Digital Detection. Dong-Ku Kang, M. Monsur Ali,Kaixiang Zhang, Susan S. Huang, Ellena Peterson, Michelle A. Digman, Enrico Gratton and Weian Zhao*. Nature Communications. (2014); Vol. 5, Issue 5427.

Featured at UCI News (1), (2).  
Also highlighted in Lab on a Chip
Research highlights: microfluidic analysis of antimicrobial susceptibility

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      1. Aptamer technology for tracking cells’ status and function. Christian Wiraja, David Yeo, Daniel Lio, Louai Labanieh, Mengrou Lu, Weian Zhao and Chenjie Xu*. Molecular and Cellular Therapies. (2014); Vol. 2, Issue 3.
        48 Aptamer technology for tracking cells status function
      1. Droplet microfluidics for single-molecule and single-cell analysis for cancer research, diagnosis and therapy. Dong-Ku Kang, M. Monsur Ali, Kaixiang Zhang, Egest J. Pone, and Weian Zhao*. Trends in Analytical Chemistry. (2014); Vol. 58: 145–153.
        article 46
      1. DNA-scaffolded multivalent ligands to modulate cell function. Zhiqing Zhang, Mark A. Eckert, M. Monsur Ali, Linan Liu, Dong-Ku Kang, Elizabeth Chang, Egest J. Pone, Leonard S. Sender, David A. Fruman, and Weian Zhao*. ChemBioChem. (2014); Vol. 15: 1268–1273.

        article 47

      1. Probe and control of cell-cell interactions using bioengineered tools. Feng Li, Rangoli Aeran, Egest J. Pone, Dong-Ku Kang, Linan Liu, X. Chris Le, and Weian Zhao*. In “Micro and Nanoengineering of the cell surface”, edited by Weian Zhao and Jeffery M. Karp, Elsevier. (2014).

        Screen Shot 2014-05-16 at 9.52.26 AM

      1. Bioengineering tools to elucidate and control the fate of transplanted cells. Rukmani Sridharan, Jeffery M. Karp, and Weian Zhao. Biochemical Society Transactions. (2014); Vol. 42: 679-687.

        44. Bioengineering tools

      1. Mesenchymal stem cells: bio-distribution, migration and homing in vivo (Editorial). Weian Zhao, Donald G. Phinney, Dominique Bonnet, Massimo Dominici, and Mauro Krampera. Stem Cells Internation. (2014); Article ID: 292109.

      1. Rolling circle amplification: a versatile tool for chemical biology, materials science and medicine. M. Monsur Ali, Feng Li, Zhiqing Zhang, Kaixiang Zhang, Dong-Ku Kang, James A. Ankrum, X. Chris Le and Weian Zhao*Chemical Society Reviews. (2014); Vol. 43: 3324-3341.

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      1. Meta-Analysis of Preclinical Studies of Mesenchymal Stromal Cells for Ischemic Stroke. Quynh Vu, Kate Xie, Mark Eckert, Weian Zhao and Steven C. Cramer. Neurology MS. (2014); Vol. 10: 1212.

2013

      1. A polyvalent aptamer system for targeted drug delivery. Zhiqing Zhang, M. Monsur Ali, Mark A. Eckert, Dong-Ku Kang, Yin Yang Chen, Leonard S. Sender, David A. Fruman, and Weian Zhao*Biomaterials. (2013); Vol. 34, Issue 37: 9728-35.

40

      1. mRNA-Engineered Mesenchymal Stem Cells for Targeted Delivery of Interleukin-10 to Sites of Inflammation. Oren Levy*, Weian Zhao*, Luke Mortensen, Sarah LeBlanc, Kyle Tsang, Moyu Fu, Joseph Phillips, Vinay Sagar, Priya Anandakumaran, essica Ngai, Cheryl Cui, Peter Eimon, Mattew Angel, Charles Lin, Mehmet Fatih Yanik, and Jeffrey Karp. Blood (2013); Vol. 122, Issue 14: 23-32. 

Check out the news release about this work at Science Daily!

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      1. From Blood to the Brain: Can Systemically ,Transplanted Mesenchymal Stem Cells Cross the Blood-Brain Barrier?. Linan Liu, Mark Eckert, Milad Riazifar, Dong-Ku Kang, Dritan Agalliu, and Weian Zhao*. Stem Cells International. (2013); Article ID: 435093.

38

      1. Novel molecular and nanosensors for in vivo sensing. Mark A. Eckert, Priscilla Q. Vu, Kaixiang Zhang, Dong-Ku Kang, M. Monsur Ali, Chenjie Xu, and Weian Zhao*Theranostics. (2013); Vol. 3, Issue 8: 583-594.

371

      1. Nanoparticle-based Monitoring of Stem Cell Therapy. Chenjie Xu and Weian Zhao*. Theranostics. (2013); Vol. 3, Issue 8: 616-617.

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      1. To grab the stroma by the horns: From biology to cancer therapy with mesenchymal stem cells. Ilia A. Droujinine, Mark A. Eckert, and Weian Zhao*. Oncotarget. (2013); Vol. 4: 651-664.

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      1. Evidence for High Translational Potential of Mesenchymal Stromal Cell Therapy to Improve Recovery from Ischemic Stroke. Mark A. Eckert, Quynh Vu, Kate Xie, Jingxia Yu, Wenbin Liao, Steven C. Cramer* and Weian Zhao*. Journal of Cerebral Blood Flow & Metabolism. (2013); Vol. 33: 1322-1334.

34

      1. Opening windows on new biology and disease mechanisms: development of real-time in vivo sensors. Mark A. Eckert and Weian Zhao*. Interface Focus. (2013); Vol. 3, Issue 3.

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      1. Microfluidic devices for biomedical applications. Dong-Ku Kang, Jenta Lu, Wenwen Zhang, Elizabeth Chang, Mark A. Eckert, M. Monsur Ali, and Weian Zhao*. Woodhead Publishing. Invited book chapter (2013).

2012

      1. Bioinspired multivalent DNA network for capture and release of cells. Weian Zhao, Cheryl H. Cui, Suman Bose, Dagang Guo, Chong Shen, Wesley P. Wong, Ken Halvorsen, Omid C. Farokhzad, Grace Sock Leng Teo, Joseph A. Phillips, David M. Dorfman, Rohit Karnik, and Jeffrey M. Karp. PNAS. (2012); Vol. .

      1. Tracking Mesenchymal Stem Cells with Iron Oxide Nanoparticle Loaded Poly(lactide-co-glycolide) Microparticles. Chenjie Xu, David Miranda-Nieves, James A. Ankrum, Mads Emil Matthiesen, Joseph A. Phillips, Isaac Roes, Gregory R. Wojtkiewicz, Vikram Juneja, Jens Roat Kultima, Weian Zhao, Praveen Kumar Vemula, Charles P. Lin, Matthias Nahrendorf, and Jeffrey M. Karp. Nano Letters. (2012); Vol. 12: 4131-4139.

      1. Cell Surface Sensors: Lightning the Cellular Environment. M. Monsur Ali, Dong-Ku Kang, Kyle Tsang, Moyu Fu, Jeffrey M. Karp, and Weian Zhao*. WIREs: Naomedicine and Nanobiotechnology. (2012); Vol. 4, Issue 5: 547-561.

      1. Colorimetric and Ultrasensitive Bioassay Based on a Dual-Amplification System Using Aptamer and DNAzyme. Longhua Tang, Yang Liu, M. Monsur Ali, Kong-Ku Kang, Weian Zhao*, and Jinghong Li*. Analytical Chemistry. (2012); Vol. 84, Issue 11: 4711-4717.

2011 And Before

      1. Bioengineering nanotechnology: towards the clinic. Weian Zhao, Jeffery M. Karp, Mauro Ferrari, and Rita Serda. Nanotechnology. (2011); Vol. 22, Issue 49.

      1. Engineered cell homing. Debanjan Sarkar, Joel A. Spencer, Joseph A. Phillips, Weian Zhao, Sebastian Schafer, Dawn P. Spelke, Luke J. Mortensen, Juan P. Ruiz, Praveen Kumar Vemula, Rukmani Sridharan, Sriram Kumar, Rohit Karnik, Charles P. Lin, and Jeffrey M. Karp. Blood. (2011); Vol 118: 184-191.

      1. Nanoparticle-based Imaging Probes. Chenjie Xu, Luye Mu, Isaac Roes, David Miranda-Nieves, Weian Zhao, and Jeffrey M. Karp. Nanotechnology. (2011); Vol. 22, Issue 49.  

(Special Issue of Bioengineered Nanotechnology). doi: 10.1088/0957-4484/22/49/494001

      1. Cell surface sensors for real-time probing of cellular environments. Weian Zhao, Sebastian Schafer, Jonghoon Choi, Yvonne J. Yamanaka, Maria L. Lombardi, Suman Bose, Alicia L. Carlson, Joseph A. Phillips, Weisuong Teo, Ilia A. Droujinine, Cheryl Cui, Rakesh K. Jain, Jan Lammerding, J. Christopher Love, Charles P. Lin, Debanjan Sarkar, Rohit Karnik, and Jeffrey M. Karp*. Nature Nanotechnology. (2011); Vol. 6: 524-531.

Highlighted in Nature Biotechnology News Article

      1. Mimicking the inflammatory cell adhesion cascade by nucleic acid aptamer programmed cell-cell interactions. Weian Zhao, Weili Loh, Ilia A. Droujinine, Weisuong Teo, Namit Kumar, Sebastian Schafer, Cheryl Cui, Liang Zhang, Debanjan Sarkar, Rohit Karnik and Jeffrey M. Karp*. The FASEB Journal. (2011); Vol. 25, Issue 9: 3045-3056.

      1. Cell surface engineering of mesenchymal stem cell. Debanjan Sarkar, Weian Zhao, Ashish Gupta, Weili Loh, Rohit Karnik, and Jeffrey M. Karp*. “Mesenchymal stem cell assays and applications in The Methods in Molecular Biology series” by Humana Press. (2011) Vol. 698: 505-523.

22

      1. Chemistry and material science at the cell surface. Weian Zhao, Grace Teo, Namit Kumar, and Jeffrey M. Karp*. Materials Today. (2010); Vol. 13: 14-21.

      1. Stem cell homing to sites of injury and inflammation. Weian Zhao, James Ankrum, Debanjan Sarkar, Weisoung Teo, Namit Kumar, and Jeffrey M Karp*. Stem Cells and Neovascularization in Tissue Engineering, Taylor & Francis. (2011); Vol. 217.

      1. Therapeutic applications of mesenchymal stem cells. Weian Zhao, Debanjan Sarkar, Sean Hall, James Ankrum, Weili Loh, Wei Suong Teo, and Jeffrey M. Karp*. Stem Cells & Regenerative Medicine, Springer/Humana. (2010); 195-218.

      1. Engineered mesenchymal stem cells with self-assembled vesicles for systemic cell targeting. Debanjan Sarkar, Praveen Kumar Vemula, Weian Zhao, Ashish Gupta, and Jeffrey M. Karp*. Biomaterials. (2010); Vol. 31: 5266-5274.

      1. Novel Implantable vein graft contrast yields enhanced outer wall definition in magnetic resonance imaging. C. Keith Ozaki*, Dimitrios Mitsouras, Praveen K. Vemula, Dia Smiley, Ming Tao, Peng Yu, Christina Campagna, Weian Zhao, Robert V. Mulkern, Jeffrey M. Karp, and Frank Rybicki. Journal of Vascular Surgery. (2010); Vol. 51: 533.

      1. Applications of Biomaterials in Functional Tissue Engineering. Debanjan Sarkar, Weian Zhao, Sebastian Schaefer, James Ankrum, Weili Teo, and Jeffrey M. Karp. Biomaterials Science: An Introduction to Materials in Medicine 3rd Edition. Invited for publication by Academic Press, (2009).

      1. Control cell fate in vivo. Weian Zhao and Jeffrey M. Karp*. ChemBioChem. (2009); Vol. 10: 2308-2310.

      1. Tumor targeting: Nanoantennas heat up. Weian Zhao and Jeffrey M. Karp.* Nature Materials. (2009); Vol. 8: 453-454.

News and Views article in Special issue on biomaterials.

      1. Covalent assembly of silica nanoparticle aggregates for oligonucleotide synthesis. Weian Zhao, Elodie Pacard, Carole Chaix-Bauvais, Christian Pichot, and Michael A. Brook. Colloids and Surfaces A. (2009); Vol. 339, Issue 1-3: 26-34.

      1. Lab on Paper. Weian Zhao* and Albert van der Berg*. Lab Chip. Commentary article in Special Issue on point-of-care diagnostics (2008); Vol. 8: 1988-1991.

      1. Paper-based bioassays using gold nanoparticle colorimetric probes. Weian Zhao, Monsur M. Ali, Sergio D. Aguirre, Michael A. Brook* and Yingfu Li*. Analytical Chemistry. (2008); Vol. 80: 8431-8437.

      1. Design of gold nanoparticle based colorimetric biosensing assays. Weian Zhao, Michael A. Brook*, and Yingfu Li*. ChembioChem. (2008); Vol. 9: 2363-71. Review article.

        Most accessed articles in 2008-2009
        Most cited in 2010

      1. Rolling circle amplification: new applications in nanotechnology and functional nucleic acid-based biodection. Weian Zhao, Monsur M. Ali, Michael A. Brook* and Yingfu Li*. Angewandte Chemistry International Edition. (2008); Vol. 47: 6330-6337

      1. DNA aptamer folding on gold nanoparticle: from colloid chemistry to biosensors. Weian Zhao, William Chiuman, Jeffrey C. F. Lam, Simon A. McManus, Wei Chen, Yuguo Cui, Robert Pelton, Michael A. Brook*, and Yingfu Li*. Journal of the American Chemical Society. (2008); Vol. 130: 3610-3618.

Selected as one of 21 papers of “chemistry at nano and bio interface”.

      1. Enzymatic cleavage of nucleic acid on gold nanoparticle: a generic platform for facile biosensors. Weian Zhao, Jeffrey C. F. Lam, Willium Chiuman, Michael A. Brook*, and Yingfu Li*. Small. (2008); Vol. 4: 810-816.

      1. Periodic assembly of nanospecies on repetitive DNA generated on gold nanoparticles by rolling circle amplification. Weian Zhao, Michael A. Brook, and Yingfu Li*. Nanostructure Design Methods and Protocols, The Methods in Molecular Biology series by Humana Press. (2008); 79-90.

6

      1. Simple and rapid colorimetric biosensors based on DNA aptamer and non-crosslinking gold nanoparticle aggregation. Weian Zhao, William Chiuman, Michael A. Brook*, and Yingfu Li*. ChemBioChem. (2007) Vol. 8: 727-731.

Most accessed articles in 2007.

      1. Highly stabilized nucleotide-capped small gold nanoparticles with tunable size. Weian Zhao, Ferdinand Gonzaga, Yingfu Li*, and Michael A. Brook*. Advanced Materials. (2007); Vol. 19: 1766-1771.

      1. Simple and rapid colorimetric enzyme sensing assays using non-crosslinking gold nanoparticle aggregation. Weian Zhao, William Chiuman, Jeffrey Lam, Michael A. Brook*, and Yingfu Li*. Chemical Communications. (2007); Vol. 36: 3729-3731.

      1. Wrapping single-walled carbon nanotubes with long single-stranded DNA molecules produced by rolling circle amplification. Weian Zhao, Yan Gao, Michael A. Brook*, and Yingfu Li*. Chemical Communications. (2006); Vol. 34: 3582-3584.

      1. DNA polymerization on gold nanoparticles through rolling circle amplification: towards novel scaffolds for three-dimensional periodic nanoassemblies. Weian Zhao, Yan Gao, Srinivas A. Kandadai, Michael A. Brook*, and Yingfu Li*. Angewandte Chemie International Edition. (2006); Vol. 45: 2409-2413.

        (VIP paper) Highlighted in MRS bulletin.
        News Release: Hula-Hoop Nanotechnique